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teng-gao committed Sep 19, 2024
2 parents e5f3df7 + c9f0c0e commit 2827ebc
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8 changes: 4 additions & 4 deletions DESCRIPTION
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Package: numbat
Title: Haplotype-Aware CNV Analysis from scRNA-Seq
URL: https://github.com/kharchenkolab/numbat/, https://kharchenkolab.github.io/numbat/
Version: 1.4.1
Authors@R: c(person("Teng","Gao", email="[email protected]", role=c("cre", "aut")), person("Ruslan", "Soldatov", email="[email protected]", role="aut"), person("Hirak", "Sarkar", email="[email protected]", role="aut"), person("Evan", "Biederstedt", email="[email protected]", role="aut"), person("Peter", "Kharchenko", email = "[email protected]", role = "aut"))
Version: 1.4.2
Authors@R: c(person("Teng","Gao", email="[email protected]", role=c("cre", "aut")), person("Ruslan", "Soldatov", email="[email protected]", role="aut"), person("Hirak", "Sarkar", email="[email protected]", role="aut"), person("Evan", "Biederstedt", email="[email protected]", role="aut"), person("Peter", "Kharchenko", email = "[email protected]", role = "aut"))
Description: A computational method that infers copy number variations (CNVs) in cancer scRNA-seq data and reconstructs the tumor phylogeny. 'numbat' integrates signals from gene expression, allelic ratio, and population haplotype structures to accurately infer allele-specific CNVs in single cells and reconstruct their lineage relationship. 'numbat' can be used to: 1. detect allele-specific copy number variations from single-cells; 2. differentiate tumor versus normal cells in the tumor microenvironment; 3. infer the clonal architecture and evolutionary history of profiled tumors. 'numbat' does not require tumor/normal-paired DNA or genotype data, but operates solely on the donor scRNA-data data (for example, 10x Cell Ranger output). Additional examples and documentations are available at <https://kharchenkolab.github.io/numbat/>. For details on the method please see Gao et al. Nature Biotechnology (2022) <doi:10.1038/s41587-022-01468-y>.
License: MIT + file LICENSE
Encoding: UTF-8
Expand All @@ -15,7 +15,7 @@ Imports:
caTools,
data.table,
dendextend,
dplyr,
dplyr (>= 1.1.1),
GenomicRanges,
ggplot2,
ggraph,
Expand All @@ -42,7 +42,7 @@ Imports:
stringr,
tibble,
tidygraph,
tidyr,
tidyr (>= 1.3.0),
vcfR,
zoo
Suggests:
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14 changes: 14 additions & 0 deletions NEWS.md
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# numbat 1.4.2 - 09/18/2023

* Fix pseudobulk plotting legend (#182)

* Requirement for dplyr and tidyr versions (#189, #190)

* Fix Numbat$plot_exp_roll (#169)

* Fix CNV states reporting when `segs_loh` is provided (#183)

* Fix `n_states` reporting (#178)

* Improve error handling in `pileup_and_phase` (#179)

# numbat 1.4.0 - 02/23/2023

* Integration with hahmmr
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3 changes: 2 additions & 1 deletion R/vis.R
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Expand Up @@ -162,7 +162,8 @@ plot_psbulk = function(
p = p + geom_point(
aes(shape = str_detect(state_post, '_2'), alpha = str_detect(state_post, '_2')),
size = dot_size,
na.rm = TRUE
na.rm = TRUE,
show.legend = TRUE
) +
geom_hline(
data = data.frame(y = c(0,1), variable = 'pHF'),
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