Ambiguous DNA bases (N, D, H, W) wrongly converted to DNA bases on antisense creation #6196
Labels
Antisense
Bucket: Antisense related issues
Priority: High
Severity: High
High level visibility to the user
Milestone
Steps to Reproduce
RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}$$$$V2.0
Actual behavior

System creates all DNA bases instead of RNA ones in antisense chain.
HELM export result:
RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}|RNA2{R(A,C,G,T)P.R(A,C,T)P.R(A,G,T)P.R(A,T)P}$RNA1,RNA2,2:pair-2:pair|RNA1,RNA2,5:pair-5:pair|RNA1,RNA2,8:pair-8:pair|RNA1,RNA2,11:pair-11:pair$$$V2.0
Expected behavior

System creates all RNA bases
HELM export result:
RNA1{R(A,C,G,T)P.R(A,G,T)P.R(A,C,T)P.R(A,T)P}|RNA2{R(A,C,G,U)P.R(A,C,U)P.R(A,G,U)P.R(A,U)P}$RNA1,RNA2,2:pair-2:pair|RNA1,RNA2,5:pair-5:pair|RNA1,RNA2,8:pair-8:pair|RNA1,RNA2,11:pair-11:pair$$$V2.0
As per requirement:
Complementary bases
Versions
Issue found while testing - #5678
The text was updated successfully, but these errors were encountered: