Data and analysis scripts for Wu, Wall, Carr et al., Lancet, 2022.
"Three-dose vaccination elicits neutralising antibodies against omicron"
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00092-7/fulltext
Please cite:
Wu M, Wall EC, Carr EJ, et al. Three-dose vaccination elicits neutralising antibodies against omicron. Lancet 2022; published online Jan 19. DOI:10.1016/S0140-6736(22)00092-7.
This publication is a third analysis of the Crick/UCLH Legacy study, and builds on previously published work:
"AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC"
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01462-8/fulltext
and incorporating data from Wall, Wu, et al., Lancet, 2021.
"Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination"
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01290-3/fulltext
These may also be cited as:
Wall EC, Wu M, Harvey R, Kelly G, Warchal S, Sawyer C, Daniels R, Adams L, Hobson P, Hatipoglu E, Ngai Y, Hussain S, Ambrose K, Hindmarsh S, Beale R, Riddell A, Gamblin S, Howell M, Kassiotis G, Libri V, Williams B, Swanton C, Gandhi S, Bauer DL. AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC. Lancet. 2021 Jul 17;398(10296):207-209. doi: 10.1016/S0140-6736(21)01462-8. Epub 2021 Jun 28. PMID: 34197809; PMCID: PMC8238446.
AND
Wall EC, Wu M, Harvey R, Kelly G, Warchal S, Sawyer C, Daniels R, Hobson P, Hatipoglu E, Ngai Y, Hussain S, Nicod J, Goldstone R, Ambrose K, Hindmarsh S, Beale R, Riddell A, Gamblin S, Howell M, Kassiotis G, Libri V, Williams B, Swanton C, Gandhi S, Bauer DLV. Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination. Lancet. 2021 Jun 19;397(10292):2331-2333. doi: 10.1016/S0140-6736(21)01290-3. Epub 2021 Jun 3. PMID: 34090624; PMCID: PMC8175044.
Available in this repository:
- LegacyOmicron_19jan2022_PUBLIC.Rdata
- Crick_Legacy_Omicron1_2022-01-19_generatePlots.R
Note that the barcode/participant IDs are not in common with previous repositories.