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After #388, this will be less of an issue, since the more recent amici-petab-import will already treat petab-estimate=0 parameters as fixed parameters. What remains, is the handling of parameters w.r.t. which we only require sensitivity for certain simulation conditions. This then condition-specific amici-plist 1) needs to be written to the input files and 2) must be accounted for when aggregating the gradients from individual model simulations to the objective gradient.
…parameters
* Make use of amici::ExpData::plist to compute only relevant sensitivities for each simulation condition.
* Update logging for nplist
* Include Bruno_JExpBot2016 on GHA, which is a great test case for plist
Closes#380
…parameters
* Make use of amici::ExpData::plist to compute only relevant sensitivities for each simulation condition.
* Update logging for nplist
* Include Bruno_JExpBot2016 on GHA, which is a great test case for plist
Closes#380
…parameters
* Make use of amici::ExpData::plist to compute only relevant sensitivities for each simulation condition.
* Update logging for nplist
* Include Bruno_JExpBot2016 on GHA, which is a great test case for plist
Closes#380
... currently this is done w.r.t. all parameters.
While less performance critical with ASA, it might still result in unnecessary simulation failures due to issues during gradient computation.
Related: #190, #343
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