diff --git a/notebooks/008_application_grk/001_grk_structures_in_klifs.ipynb b/notebooks/008_application_grk/001_grk_structures_in_klifs.ipynb
new file mode 100644
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@@ -0,0 +1,689 @@
+{
+ "cells": [
+  {
+   "cell_type": "markdown",
+   "id": "de774775-ab50-4ac6-8fd1-9edbf6bdb0a2",
+   "metadata": {},
+   "source": [
+    "# GRK structures in KLIFS"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 1,
+   "id": "45f44548-22d2-45a1-8541-7200f2918477",
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "import pandas as pd\n",
+    "from opencadd.databases.klifs import setup_remote"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 2,
+   "id": "58dfff58-5843-4d23-96f1-20a9ca6b7a4d",
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "klifs_session = setup_remote()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 3,
+   "id": "b0d78c63-0cdd-4bdf-b0cf-1b6042b2ce4b",
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/html": [
+       "<div>\n",
+       "<style scoped>\n",
+       "    .dataframe tbody tr th:only-of-type {\n",
+       "        vertical-align: middle;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe tbody tr th {\n",
+       "        vertical-align: top;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe thead th {\n",
+       "        text-align: right;\n",
+       "    }\n",
+       "</style>\n",
+       "<table border=\"1\" class=\"dataframe\">\n",
+       "  <thead>\n",
+       "    <tr style=\"text-align: right;\">\n",
+       "      <th></th>\n",
+       "      <th>kinase.klifs_id</th>\n",
+       "      <th>kinase.klifs_name</th>\n",
+       "      <th>kinase.full_name</th>\n",
+       "      <th>kinase.gene_name</th>\n",
+       "      <th>kinase.uniprot</th>\n",
+       "      <th>species.klifs</th>\n",
+       "    </tr>\n",
+       "  </thead>\n",
+       "  <tbody>\n",
+       "    <tr>\n",
+       "      <th>0</th>\n",
+       "      <td>16</td>\n",
+       "      <td>RHOK</td>\n",
+       "      <td>G protein-coupled receptor kinase 1</td>\n",
+       "      <td>GRK1</td>\n",
+       "      <td>Q15835</td>\n",
+       "      <td>Human</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>1</th>\n",
+       "      <td>11</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 1</td>\n",
+       "      <td>GRK2</td>\n",
+       "      <td>P25098</td>\n",
+       "      <td>Human</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>2</th>\n",
+       "      <td>12</td>\n",
+       "      <td>BARK2</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 2</td>\n",
+       "      <td>GRK3</td>\n",
+       "      <td>P35626</td>\n",
+       "      <td>Human</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3</th>\n",
+       "      <td>13</td>\n",
+       "      <td>GPRK4</td>\n",
+       "      <td>G protein-coupled receptor kinase 4</td>\n",
+       "      <td>GRK4</td>\n",
+       "      <td>P32298</td>\n",
+       "      <td>Human</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>4</th>\n",
+       "      <td>14</td>\n",
+       "      <td>GPRK5</td>\n",
+       "      <td>G protein-coupled receptor kinase 5</td>\n",
+       "      <td>GRK5</td>\n",
+       "      <td>P34947</td>\n",
+       "      <td>Human</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>5</th>\n",
+       "      <td>15</td>\n",
+       "      <td>GPRK6</td>\n",
+       "      <td>G protein-coupled receptor kinase 6</td>\n",
+       "      <td>GRK6</td>\n",
+       "      <td>P43250</td>\n",
+       "      <td>Human</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>6</th>\n",
+       "      <td>17</td>\n",
+       "      <td>GPRK7</td>\n",
+       "      <td>G protein-coupled receptor kinase 7</td>\n",
+       "      <td>GRK7</td>\n",
+       "      <td>Q8WTQ7</td>\n",
+       "      <td>Human</td>\n",
+       "    </tr>\n",
+       "  </tbody>\n",
+       "</table>\n",
+       "</div>"
+      ],
+      "text/plain": [
+       "   kinase.klifs_id kinase.klifs_name                     kinase.full_name  \\\n",
+       "0               16              RHOK  G protein-coupled receptor kinase 1   \n",
+       "1               11             BARK1  adrenergic, beta, receptor kinase 1   \n",
+       "2               12             BARK2  adrenergic, beta, receptor kinase 2   \n",
+       "3               13             GPRK4  G protein-coupled receptor kinase 4   \n",
+       "4               14             GPRK5  G protein-coupled receptor kinase 5   \n",
+       "5               15             GPRK6  G protein-coupled receptor kinase 6   \n",
+       "6               17             GPRK7  G protein-coupled receptor kinase 7   \n",
+       "\n",
+       "  kinase.gene_name kinase.uniprot species.klifs  \n",
+       "0             GRK1         Q15835         Human  \n",
+       "1             GRK2         P25098         Human  \n",
+       "2             GRK3         P35626         Human  \n",
+       "3             GRK4         P32298         Human  \n",
+       "4             GRK5         P34947         Human  \n",
+       "5             GRK6         P43250         Human  \n",
+       "6             GRK7         Q8WTQ7         Human  "
+      ]
+     },
+     "execution_count": 3,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "kinases = klifs_session.kinases.all_kinases(families=\"GRK\", species=\"Human\")\n",
+    "kinases"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 4,
+   "id": "189c2c0c-baeb-4ac7-8de2-1d4e3c940065",
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "16 11 12 13 14 15 17\n"
+     ]
+    }
+   ],
+   "source": [
+    "kinase_klifs_ids = kinases[\"kinase.klifs_id\"].to_list()\n",
+    "print(*kinase_klifs_ids)"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 5,
+   "id": "0111493c-95ce-4ddc-8caa-b35d4c08ad19",
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/html": [
+       "<div>\n",
+       "<style scoped>\n",
+       "    .dataframe tbody tr th:only-of-type {\n",
+       "        vertical-align: middle;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe tbody tr th {\n",
+       "        vertical-align: top;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe thead th {\n",
+       "        text-align: right;\n",
+       "    }\n",
+       "</style>\n",
+       "<table border=\"1\" class=\"dataframe\">\n",
+       "  <thead>\n",
+       "    <tr style=\"text-align: right;\">\n",
+       "      <th></th>\n",
+       "      <th>kinase.klifs_id</th>\n",
+       "      <th>kinase.klifs_name</th>\n",
+       "      <th>kinase.full_name</th>\n",
+       "      <th>kinase.gene_name</th>\n",
+       "      <th>kinase.family</th>\n",
+       "      <th>kinase.group</th>\n",
+       "      <th>kinase.subfamily</th>\n",
+       "      <th>species.klifs</th>\n",
+       "      <th>kinase.uniprot</th>\n",
+       "      <th>kinase.iuphar</th>\n",
+       "      <th>kinase.pocket</th>\n",
+       "    </tr>\n",
+       "  </thead>\n",
+       "  <tbody>\n",
+       "    <tr>\n",
+       "      <th>0</th>\n",
+       "      <td>11</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 1</td>\n",
+       "      <td>GRK2</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>BARK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P25098</td>\n",
+       "      <td>1466</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>1</th>\n",
+       "      <td>12</td>\n",
+       "      <td>BARK2</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 2</td>\n",
+       "      <td>GRK3</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>BARK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P35626</td>\n",
+       "      <td>1467</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMTYACFILD...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>2</th>\n",
+       "      <td>13</td>\n",
+       "      <td>GPRK4</td>\n",
+       "      <td>G protein-coupled receptor kinase 4</td>\n",
+       "      <td>GRK4</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P32298</td>\n",
+       "      <td>1468</td>\n",
+       "      <td>RVLGKGGFGEVCAYACKKLMALNEKRILEKVQRFVVSLAYACLVLT...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3</th>\n",
+       "      <td>14</td>\n",
+       "      <td>GPRK5</td>\n",
+       "      <td>G protein-coupled receptor kinase 5</td>\n",
+       "      <td>GRK5</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P34947</td>\n",
+       "      <td>1469</td>\n",
+       "      <td>RVLGKGGFGEVCAYACKRLMALNEKQILEKVNQFVVNLAYACLVLT...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>4</th>\n",
+       "      <td>15</td>\n",
+       "      <td>GPRK6</td>\n",
+       "      <td>G protein-coupled receptor kinase 6</td>\n",
+       "      <td>GRK6</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P43250</td>\n",
+       "      <td>1470</td>\n",
+       "      <td>RVLGKGGFGEVCAYACKKLMALNEKQILEKVNRFVVSLAYACLVLT...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>5</th>\n",
+       "      <td>16</td>\n",
+       "      <td>RHOK</td>\n",
+       "      <td>G protein-coupled receptor kinase 1</td>\n",
+       "      <td>GRK1</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>Q15835</td>\n",
+       "      <td>1465</td>\n",
+       "      <td>RVLGKGGFGEVSAYACKKLGAMVEKKILMKVHRFIVSLAYACLVMT...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>6</th>\n",
+       "      <td>17</td>\n",
+       "      <td>GPRK7</td>\n",
+       "      <td>G protein-coupled receptor kinase 7</td>\n",
+       "      <td>GRK7</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>Q8WTQ7</td>\n",
+       "      <td>1471</td>\n",
+       "      <td>RVLGKGGFGEVCAYACKKLMALLEKEILEKVSPFIVSLAYACLVMS...</td>\n",
+       "    </tr>\n",
+       "  </tbody>\n",
+       "</table>\n",
+       "</div>"
+      ],
+      "text/plain": [
+       "   kinase.klifs_id kinase.klifs_name                     kinase.full_name  \\\n",
+       "0               11             BARK1  adrenergic, beta, receptor kinase 1   \n",
+       "1               12             BARK2  adrenergic, beta, receptor kinase 2   \n",
+       "2               13             GPRK4  G protein-coupled receptor kinase 4   \n",
+       "3               14             GPRK5  G protein-coupled receptor kinase 5   \n",
+       "4               15             GPRK6  G protein-coupled receptor kinase 6   \n",
+       "5               16              RHOK  G protein-coupled receptor kinase 1   \n",
+       "6               17             GPRK7  G protein-coupled receptor kinase 7   \n",
+       "\n",
+       "  kinase.gene_name kinase.family kinase.group kinase.subfamily species.klifs  \\\n",
+       "0             GRK2           GRK          AGC             BARK         Human   \n",
+       "1             GRK3           GRK          AGC             BARK         Human   \n",
+       "2             GRK4           GRK          AGC              GRK         Human   \n",
+       "3             GRK5           GRK          AGC              GRK         Human   \n",
+       "4             GRK6           GRK          AGC              GRK         Human   \n",
+       "5             GRK1           GRK          AGC              GRK         Human   \n",
+       "6             GRK7           GRK          AGC              GRK         Human   \n",
+       "\n",
+       "  kinase.uniprot kinase.iuphar  \\\n",
+       "0         P25098          1466   \n",
+       "1         P35626          1467   \n",
+       "2         P32298          1468   \n",
+       "3         P34947          1469   \n",
+       "4         P43250          1470   \n",
+       "5         Q15835          1465   \n",
+       "6         Q8WTQ7          1471   \n",
+       "\n",
+       "                                       kinase.pocket  \n",
+       "0  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...  \n",
+       "1  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMTYACFILD...  \n",
+       "2  RVLGKGGFGEVCAYACKKLMALNEKRILEKVQRFVVSLAYACLVLT...  \n",
+       "3  RVLGKGGFGEVCAYACKRLMALNEKQILEKVNQFVVNLAYACLVLT...  \n",
+       "4  RVLGKGGFGEVCAYACKKLMALNEKQILEKVNRFVVSLAYACLVLT...  \n",
+       "5  RVLGKGGFGEVSAYACKKLGAMVEKKILMKVHRFIVSLAYACLVMT...  \n",
+       "6  RVLGKGGFGEVCAYACKKLMALLEKEILEKVSPFIVSLAYACLVMS...  "
+      ]
+     },
+     "execution_count": 5,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "kinases = klifs_session.kinases.by_kinase_klifs_id(kinase_klifs_ids)\n",
+    "kinases"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 6,
+   "id": "e0e49df2-3d5c-43ce-b384-7a527569c4f2",
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "Number of GRK structures: 41\n"
+     ]
+    },
+    {
+     "data": {
+      "text/html": [
+       "<div>\n",
+       "<style scoped>\n",
+       "    .dataframe tbody tr th:only-of-type {\n",
+       "        vertical-align: middle;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe tbody tr th {\n",
+       "        vertical-align: top;\n",
+       "    }\n",
+       "\n",
+       "    .dataframe thead th {\n",
+       "        text-align: right;\n",
+       "    }\n",
+       "</style>\n",
+       "<table border=\"1\" class=\"dataframe\">\n",
+       "  <thead>\n",
+       "    <tr style=\"text-align: right;\">\n",
+       "      <th></th>\n",
+       "      <th>structure.klifs_id</th>\n",
+       "      <th>structure.pdb_id</th>\n",
+       "      <th>structure.alternate_model</th>\n",
+       "      <th>structure.chain</th>\n",
+       "      <th>species.klifs_x</th>\n",
+       "      <th>kinase.klifs_id</th>\n",
+       "      <th>kinase.klifs_name_x</th>\n",
+       "      <th>kinase.names</th>\n",
+       "      <th>structure.pocket</th>\n",
+       "      <th>ligand.expo_id</th>\n",
+       "      <th>...</th>\n",
+       "      <th>kinase.klifs_name_y</th>\n",
+       "      <th>kinase.full_name</th>\n",
+       "      <th>kinase.gene_name</th>\n",
+       "      <th>kinase.family</th>\n",
+       "      <th>kinase.group</th>\n",
+       "      <th>kinase.subfamily</th>\n",
+       "      <th>species.klifs_y</th>\n",
+       "      <th>kinase.uniprot</th>\n",
+       "      <th>kinase.iuphar</th>\n",
+       "      <th>kinase.pocket</th>\n",
+       "    </tr>\n",
+       "  </thead>\n",
+       "  <tbody>\n",
+       "    <tr>\n",
+       "      <th>0</th>\n",
+       "      <td>9440</td>\n",
+       "      <td>5wg5</td>\n",
+       "      <td>B</td>\n",
+       "      <td>A</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>11</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>&lt;NA&gt;</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "      <td>ZSO</td>\n",
+       "      <td>...</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 1</td>\n",
+       "      <td>GRK2</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>BARK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P25098</td>\n",
+       "      <td>1466</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>1</th>\n",
+       "      <td>8256</td>\n",
+       "      <td>5uvc</td>\n",
+       "      <td>-</td>\n",
+       "      <td>A</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>11</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>&lt;NA&gt;</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "      <td>8PV</td>\n",
+       "      <td>...</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 1</td>\n",
+       "      <td>GRK2</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>BARK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P25098</td>\n",
+       "      <td>1466</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>2</th>\n",
+       "      <td>9437</td>\n",
+       "      <td>5wg5</td>\n",
+       "      <td>A</td>\n",
+       "      <td>A</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>11</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>&lt;NA&gt;</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "      <td>ZSO</td>\n",
+       "      <td>...</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 1</td>\n",
+       "      <td>GRK2</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>BARK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P25098</td>\n",
+       "      <td>1466</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>3</th>\n",
+       "      <td>9438</td>\n",
+       "      <td>5wg4</td>\n",
+       "      <td>B</td>\n",
+       "      <td>A</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>11</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>&lt;NA&gt;</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "      <td>AFV</td>\n",
+       "      <td>...</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 1</td>\n",
+       "      <td>GRK2</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>BARK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P25098</td>\n",
+       "      <td>1466</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "    </tr>\n",
+       "    <tr>\n",
+       "      <th>4</th>\n",
+       "      <td>9439</td>\n",
+       "      <td>5wg3</td>\n",
+       "      <td>-</td>\n",
+       "      <td>A</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>11</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>&lt;NA&gt;</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "      <td>AFM</td>\n",
+       "      <td>...</td>\n",
+       "      <td>BARK1</td>\n",
+       "      <td>adrenergic, beta, receptor kinase 1</td>\n",
+       "      <td>GRK2</td>\n",
+       "      <td>GRK</td>\n",
+       "      <td>AGC</td>\n",
+       "      <td>BARK</td>\n",
+       "      <td>Human</td>\n",
+       "      <td>P25098</td>\n",
+       "      <td>1466</td>\n",
+       "      <td>RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...</td>\n",
+       "    </tr>\n",
+       "  </tbody>\n",
+       "</table>\n",
+       "<p>5 rows × 54 columns</p>\n",
+       "</div>"
+      ],
+      "text/plain": [
+       "   structure.klifs_id structure.pdb_id structure.alternate_model  \\\n",
+       "0                9440             5wg5                         B   \n",
+       "1                8256             5uvc                         -   \n",
+       "2                9437             5wg5                         A   \n",
+       "3                9438             5wg4                         B   \n",
+       "4                9439             5wg3                         -   \n",
+       "\n",
+       "  structure.chain species.klifs_x  kinase.klifs_id kinase.klifs_name_x  \\\n",
+       "0               A           Human               11               BARK1   \n",
+       "1               A           Human               11               BARK1   \n",
+       "2               A           Human               11               BARK1   \n",
+       "3               A           Human               11               BARK1   \n",
+       "4               A           Human               11               BARK1   \n",
+       "\n",
+       "  kinase.names                                   structure.pocket  \\\n",
+       "0         <NA>  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...   \n",
+       "1         <NA>  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...   \n",
+       "2         <NA>  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...   \n",
+       "3         <NA>  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...   \n",
+       "4         <NA>  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...   \n",
+       "\n",
+       "  ligand.expo_id  ... kinase.klifs_name_y  \\\n",
+       "0            ZSO  ...               BARK1   \n",
+       "1            8PV  ...               BARK1   \n",
+       "2            ZSO  ...               BARK1   \n",
+       "3            AFV  ...               BARK1   \n",
+       "4            AFM  ...               BARK1   \n",
+       "\n",
+       "                      kinase.full_name  kinase.gene_name kinase.family  \\\n",
+       "0  adrenergic, beta, receptor kinase 1              GRK2           GRK   \n",
+       "1  adrenergic, beta, receptor kinase 1              GRK2           GRK   \n",
+       "2  adrenergic, beta, receptor kinase 1              GRK2           GRK   \n",
+       "3  adrenergic, beta, receptor kinase 1              GRK2           GRK   \n",
+       "4  adrenergic, beta, receptor kinase 1              GRK2           GRK   \n",
+       "\n",
+       "  kinase.group kinase.subfamily species.klifs_y  kinase.uniprot  \\\n",
+       "0          AGC             BARK           Human          P25098   \n",
+       "1          AGC             BARK           Human          P25098   \n",
+       "2          AGC             BARK           Human          P25098   \n",
+       "3          AGC             BARK           Human          P25098   \n",
+       "4          AGC             BARK           Human          P25098   \n",
+       "\n",
+       "   kinase.iuphar                                      kinase.pocket  \n",
+       "0           1466  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...  \n",
+       "1           1466  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...  \n",
+       "2           1466  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...  \n",
+       "3           1466  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...  \n",
+       "4           1466  RIIGRGGFGEVYGYAMKCLLALNERIMLSLVSPFIVCMSYASFILD...  \n",
+       "\n",
+       "[5 rows x 54 columns]"
+      ]
+     },
+     "execution_count": 6,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "structures = klifs_session.structures.by_kinase_klifs_id(kinase_klifs_ids)\n",
+    "structures = pd.merge(\n",
+    "    structures.drop([\"kinase.family\", \"kinase.group\"], axis=1), kinases, on=[\"kinase.klifs_id\"]\n",
+    ")\n",
+    "print(f\"Number of GRK structures: {len(structures)}\")\n",
+    "structures.head()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 7,
+   "id": "c9ba7827-1796-4a15-835f-3dcfb3f7f4e0",
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "Number of KLIFS structures per kinase\n"
+     ]
+    },
+    {
+     "data": {
+      "text/plain": [
+       "kinase.gene_name\n",
+       "GRK2    29\n",
+       "GRK4     2\n",
+       "GRK5     4\n",
+       "GRK6     6\n",
+       "dtype: int64"
+      ]
+     },
+     "execution_count": 7,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "print(\"Number of KLIFS structures per kinase\")\n",
+    "structures.groupby(\"kinase.gene_name\").size()"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": null,
+   "id": "96309789-cd99-4e5a-ad39-628e2f5bd753",
+   "metadata": {},
+   "outputs": [],
+   "source": []
+  }
+ ],
+ "metadata": {
+  "kernelspec": {
+   "display_name": "Python 3 (ipykernel)",
+   "language": "python",
+   "name": "python3"
+  },
+  "language_info": {
+   "codemirror_mode": {
+    "name": "ipython",
+    "version": 3
+   },
+   "file_extension": ".py",
+   "mimetype": "text/x-python",
+   "name": "python",
+   "nbconvert_exporter": "python",
+   "pygments_lexer": "ipython3",
+   "version": "3.9.12"
+  }
+ },
+ "nbformat": 4,
+ "nbformat_minor": 5
+}
diff --git a/notebooks/008_application_grk/README.md b/notebooks/008_application_grk/README.md
new file mode 100644
index 0000000..0c0c958
--- /dev/null
+++ b/notebooks/008_application_grk/README.md
@@ -0,0 +1,3 @@
+## `001_grk_structures_in_klifs.ipynb`
+
+GRK structures in KLIFS