diff --git a/bisect/43336.py b/bisect/43336.py
new file mode 100644
index 0000000000000..128454ab0498f
--- /dev/null
+++ b/bisect/43336.py
@@ -0,0 +1,12 @@
+# BUG: Change in index of empty dataframes in mode operation #43336
+
+import pandas as pd
+
+print(pd.__version__)
+
+df = pd.DataFrame({"a": ["a", "b", "a"]}, index=["a", "b", "c"])
+result = df.mode(numeric_only=True)
+print(result)
+
+expected = pd.DataFrame(index=["a", "b", "c"])
+pd.testing.assert_frame_equal(result, expected)