diff --git a/runner/fixture.js b/runner/fixture.js
index f56aa1239..a8048481c 100644
--- a/runner/fixture.js
+++ b/runner/fixture.js
@@ -20,7 +20,7 @@ import { window, document } from "../src/globals";
 
 		var fixture = document.getElementById( "qunit-fixture" );
 		if ( fixture ) {
-			config.fixture = fixture.innerHTML;
+			config.fixture = fixture.cloneNode( true );
 		}
 	}
 
@@ -33,8 +33,14 @@ import { window, document } from "../src/globals";
 		}
 
 		var fixture = document.getElementById( "qunit-fixture" );
-		if ( fixture ) {
+		var resetFixtureType = typeof config.fixture;
+		if ( resetFixtureType === "string" ) {
+
+			// support user defined values for `config.fixture`
 			fixture.innerHTML = config.fixture;
+		} else {
+			const clonedFixture = config.fixture.cloneNode( true );
+			fixture.parentNode.replaceChild( clonedFixture, fixture );
 		}
 	}
 
diff --git a/test/main/test.js b/test/main/test.js
index c5be97ede..38a5e1277 100644
--- a/test/main/test.js
+++ b/test/main/test.js
@@ -24,6 +24,11 @@ if ( typeof document !== "undefined" ) {
 			originalValue = QUnit.config.fixture;
 			values.unshift( originalValue );
 			values.unshift( originalValue );
+
+			var customFixtureNode = document.createElement( "span" );
+			customFixtureNode.setAttribute( "id", "qunit-fixture" );
+			customFixtureNode.setAttribute( "data-baz", "huzzah!" );
+			values.push( customFixtureNode );
 		} );
 
 		hooks.beforeEach( function( assert ) {
@@ -74,7 +79,7 @@ if ( typeof document !== "undefined" ) {
 		} );
 
 		QUnit.test( "setup", function( assert ) {
-			assert.equal( values.length, 4, "proper sequence" );
+			assert.equal( values.length, 5, "proper sequence" );
 
 			// setup for next test
 			document.getElementById( "qunit-fixture" ).innerHTML = "foo";
@@ -84,9 +89,9 @@ if ( typeof document !== "undefined" ) {
 			assert.fixtureEquals( {
 				tagName: "div",
 				attributes: { id: "qunit-fixture" },
-				content: originalValue
+				content: originalValue.innerHTML
 			} );
-			assert.equal( values.length, 3, "proper sequence" );
+			assert.equal( values.length, 4, "proper sequence" );
 
 			// setup for next test
 			document.getElementById( "qunit-fixture" ).setAttribute( "data-foo", "blah" );
@@ -96,29 +101,40 @@ if ( typeof document !== "undefined" ) {
 			assert.fixtureEquals( {
 				tagName: "div",
 				attributes: { id: "qunit-fixture" },
-				content: originalValue
+				content: originalValue.innerHTML
 			} );
-			assert.equal( values.length, 2, "proper sequence" );
+			assert.equal( values.length, 3, "proper sequence" );
 		} );
 
-		QUnit.test( "user-specified", function( assert ) {
+		QUnit.test( "user-specified string", function( assert ) {
 			assert.fixtureEquals( {
 				tagName: "div",
 				attributes: { id: "qunit-fixture" },
 				content: "<b>ar</b>"
 			} );
-			assert.equal( values.length, 1, "proper sequence" );
+			assert.equal( values.length, 2, "proper sequence" );
 
 			// setup for next test
 			document.getElementById( "qunit-fixture" ).innerHTML = "baz";
 		} );
-
 		QUnit.test( "disabled", function( assert ) {
 			assert.fixtureEquals( {
 				tagName: "div",
 				attributes: { id: "qunit-fixture" },
 				content: "baz"
 			} );
+			assert.equal( values.length, 1, "proper sequence" );
+		} );
+
+		QUnit.test( "user-specified DOM node", function( assert ) {
+			assert.fixtureEquals( {
+				tagName: "span",
+				attributes: {
+					id: "qunit-fixture",
+					"data-baz": "huzzah!"
+				},
+				content: ""
+			} );
 			assert.equal( values.length, 0, "proper sequence" );
 		} );
 	} );