diff --git a/src/platform/OpenThread/GenericThreadStackManagerImpl_OpenThread.hpp b/src/platform/OpenThread/GenericThreadStackManagerImpl_OpenThread.hpp
index 35c547f4d52d25..1b7f1c52deeaa9 100644
--- a/src/platform/OpenThread/GenericThreadStackManagerImpl_OpenThread.hpp
+++ b/src/platform/OpenThread/GenericThreadStackManagerImpl_OpenThread.hpp
@@ -1220,6 +1220,7 @@ void GenericThreadStackManagerImpl_OpenThread<ImplClass>::_ErasePersistentInfo(v
     ChipLogProgress(DeviceLayer, "Erasing Thread persistent info...");
     Impl()->LockThreadStack();
     otThreadSetEnabled(mOTInst, false);
+    otIp6SetEnabled(mOTInst, false);
     otInstanceErasePersistentInfo(mOTInst);
     Impl()->UnlockThreadStack();
 }