diff --git a/dbms/src/Debug/dbgFuncMockRaftSnapshot.cpp b/dbms/src/Debug/dbgFuncMockRaftSnapshot.cpp
index cc762d2b4f5..9835b6d0ea3 100644
--- a/dbms/src/Debug/dbgFuncMockRaftSnapshot.cpp
+++ b/dbms/src/Debug/dbgFuncMockRaftSnapshot.cpp
@@ -525,7 +525,7 @@ RegionPtrWithBlock::CachePtr GenRegionPreDecodeBlockData(const RegionPtr & regio
         if (auto pd_client = tmt.getPDClient(); !pd_client->isMock())
         {
             gc_safe_point
-                = PDClientHelper::getGCSafePointWithRetry(pd_client, false, context.getSettingsRef().safe_point_update_interval_seconds);
+                = PDClientHelper::getGCSafePointWithRetry(pd_client, keyspace_id, false, context.getSettingsRef().safe_point_update_interval_seconds);
         }
         /**
          * In 5.0.1, feature `compaction filter` is enabled by default. Under such feature tikv will do gc in write & default cf individually.
diff --git a/dbms/src/Debug/dbgFuncSchema.cpp b/dbms/src/Debug/dbgFuncSchema.cpp
index 51b6f657be9..063ae9e0736 100644
--- a/dbms/src/Debug/dbgFuncSchema.cpp
+++ b/dbms/src/Debug/dbgFuncSchema.cpp
@@ -181,7 +181,7 @@ void dbgFuncGcSchemas(Context & context, const ASTs & args, DBGInvoker::Printer
     auto & service = context.getSchemaSyncService();
     Timestamp gc_safe_point = 0;
     if (args.empty())
-        gc_safe_point = PDClientHelper::getGCSafePointWithRetry(context.getTMTContext().getPDClient());
+        gc_safe_point = PDClientHelper::getGCSafePointWithRetry(context.getTMTContext().getPDClient(), NullspaceID);
     else
         gc_safe_point = safeGet<Timestamp>(typeid_cast<const ASTLiteral &>(*args[0]).value);
     service->gc(gc_safe_point, NullspaceID);
diff --git a/dbms/src/Server/Server.cpp b/dbms/src/Server/Server.cpp
index b504aef7a26..85f9e96b99a 100644
--- a/dbms/src/Server/Server.cpp
+++ b/dbms/src/Server/Server.cpp
@@ -86,6 +86,7 @@
 #include <Storages/System/attachSystemTables.h>
 #include <Storages/Transaction/FileEncryption.h>
 #include <Storages/Transaction/KVStore.h>
+#include <Storages/Transaction/PDTiKVClient.h>
 #include <Storages/Transaction/ProxyFFI.h>
 #include <Storages/Transaction/TMTContext.h>
 #include <Storages/registerStorages.h>
@@ -968,6 +969,9 @@ int Server::main(const std::vector<std::string> & /*args*/)
 
     LOG_INFO(log, "Using api_version={}", storage_config.api_version);
 
+    // Set whether to use safe point v2.
+    PDClientHelper::enable_safepoint_v2 = config().getBool("enable_safe_point_v2", false);
+
     // Init Proxy's config
     TiFlashProxyConfig proxy_conf(config(), storage_config.s3_config.isS3Enabled());
     EngineStoreServerWrap tiflash_instance_wrap{};
diff --git a/dbms/src/Storages/DeltaMerge/DeltaMergeStore_InternalBg.cpp b/dbms/src/Storages/DeltaMerge/DeltaMergeStore_InternalBg.cpp
index 4fc97e3cf76..20c6c17d98d 100644
--- a/dbms/src/Storages/DeltaMerge/DeltaMergeStore_InternalBg.cpp
+++ b/dbms/src/Storages/DeltaMerge/DeltaMergeStore_InternalBg.cpp
@@ -344,6 +344,7 @@ bool DeltaMergeStore::updateGCSafePoint()
     {
         auto safe_point = PDClientHelper::getGCSafePointWithRetry(
             pd_client,
+            keyspace_id,
             /* ignore_cache= */ false,
             global_context.getSettingsRef().safe_point_update_interval_seconds);
         latest_gc_safe_point.store(safe_point, std::memory_order_release);
diff --git a/dbms/src/Storages/StorageDeltaMerge.cpp b/dbms/src/Storages/StorageDeltaMerge.cpp
index 0b710b099de..a73676d8e52 100644
--- a/dbms/src/Storages/StorageDeltaMerge.cpp
+++ b/dbms/src/Storages/StorageDeltaMerge.cpp
@@ -624,7 +624,7 @@ void setColumnsToRead(const DeltaMergeStorePtr & store, ColumnDefines & columns_
 }
 
 // Check whether tso is smaller than TiDB GcSafePoint
-void checkReadTso(UInt64 read_tso, const Context & context, const String & req_id)
+void checkReadTso(UInt64 read_tso, const Context & context, const String & req_id, KeyspaceID keyspace_id)
 {
     auto & tmt = context.getTMTContext();
     RUNTIME_CHECK(tmt.isInitialized());
@@ -633,6 +633,7 @@ void checkReadTso(UInt64 read_tso, const Context & context, const String & req_i
         return;
     auto safe_point = PDClientHelper::getGCSafePointWithRetry(
         pd_client,
+        keyspace_id,
         /* ignore_cache= */ false,
         context.getSettingsRef().safe_point_update_interval_seconds);
     if (read_tso < safe_point)
@@ -655,7 +656,8 @@ DM::RowKeyRanges StorageDeltaMerge::parseMvccQueryInfo(
 {
     LOG_DEBUG(tracing_logger, "Read with tso: {}", mvcc_query_info.read_tso);
 
-    checkReadTso(mvcc_query_info.read_tso, context, req_id);
+    auto keyspace_id = getTableInfo().getKeyspaceID();
+    checkReadTso(mvcc_query_info.read_tso, context, req_id, keyspace_id);
 
     FmtBuffer fmt_buf;
     if (unlikely(tracing_logger->is(Poco::Message::Priority::PRIO_TRACE)))
@@ -935,8 +937,9 @@ BlockInputStreams StorageDeltaMerge::read(
         extra_table_id_index,
         scan_context);
 
+    auto keyspace_id = getTableInfo().getKeyspaceID();
     /// Ensure read_tso info after read.
-    checkReadTso(mvcc_query_info.read_tso, context, query_info.req_id);
+    checkReadTso(mvcc_query_info.read_tso, context, query_info.req_id, keyspace_id);
 
     LOG_TRACE(tracing_logger, "[ranges: {}] [streams: {}]", ranges.size(), streams.size());
 
@@ -1006,8 +1009,9 @@ void StorageDeltaMerge::read(
         extra_table_id_index,
         scan_context);
 
+    auto keyspace_id = getTableInfo().getKeyspaceID();
     /// Ensure read_tso info after read.
-    checkReadTso(mvcc_query_info.read_tso, context, query_info.req_id);
+    checkReadTso(mvcc_query_info.read_tso, context, query_info.req_id, keyspace_id);
 
     LOG_TRACE(tracing_logger, "[ranges: {}] [concurrency: {}]", ranges.size(), group_builder.concurrency());
 }
@@ -1043,8 +1047,9 @@ StorageDeltaMerge::writeNodeBuildRemoteReadSnapshot(
 
     snap->column_defines = std::make_shared<ColumnDefines>(columns_to_read);
 
+    auto keyspace_id = getTableInfo().getKeyspaceID();
     // Ensure read_tso is valid after snapshot is built
-    checkReadTso(mvcc_query_info.read_tso, context, query_info.req_id);
+    checkReadTso(mvcc_query_info.read_tso, context, query_info.req_id, keyspace_id);
     return snap;
 }
 
diff --git a/dbms/src/Storages/Transaction/ApplySnapshot.cpp b/dbms/src/Storages/Transaction/ApplySnapshot.cpp
index 7a9e7bdef4d..e450d951dd1 100644
--- a/dbms/src/Storages/Transaction/ApplySnapshot.cpp
+++ b/dbms/src/Storages/Transaction/ApplySnapshot.cpp
@@ -355,6 +355,7 @@ std::vector<DM::ExternalDTFileInfo> KVStore::preHandleSSTsToDTFiles(
             if (auto pd_client = tmt.getPDClient(); !pd_client->isMock())
             {
                 gc_safepoint = PDClientHelper::getGCSafePointWithRetry(pd_client,
+                                                                       keyspace_id,
                                                                        /* ignore_cache= */ false,
                                                                        context.getSettingsRef().safe_point_update_interval_seconds);
             }
diff --git a/dbms/src/Storages/Transaction/PDTiKVClient.cpp b/dbms/src/Storages/Transaction/PDTiKVClient.cpp
index ed46aeb18c2..bbf2a913593 100644
--- a/dbms/src/Storages/Transaction/PDTiKVClient.cpp
+++ b/dbms/src/Storages/Transaction/PDTiKVClient.cpp
@@ -25,4 +25,9 @@ extern const int LOGICAL_ERROR;
 std::atomic<Timestamp> PDClientHelper::cached_gc_safe_point = 0;
 std::atomic<std::chrono::time_point<std::chrono::steady_clock>> PDClientHelper::safe_point_last_update_time;
 
+// Keyspace gc safepoint cache and update time.
+bool PDClientHelper::enable_safepoint_v2 = false;
+std::unordered_map<KeyspaceID, KeyspaceGCInfo> PDClientHelper::ks_gc_sp_map;
+std::shared_mutex PDClientHelper::ks_gc_sp_mutex;
+
 } // namespace DB
diff --git a/dbms/src/Storages/Transaction/PDTiKVClient.h b/dbms/src/Storages/Transaction/PDTiKVClient.h
index f1be9a0a5c0..3c199e11b82 100644
--- a/dbms/src/Storages/Transaction/PDTiKVClient.h
+++ b/dbms/src/Storages/Transaction/PDTiKVClient.h
@@ -20,6 +20,7 @@
 #ifdef __clang__
 #pragma GCC diagnostic ignored "-Wdeprecated-declarations"
 #endif
+#include <Common/Logger.h>
 #include <Core/Types.h>
 #include <pingcap/kv/RegionClient.h>
 #include <pingcap/pd/IClient.h>
@@ -31,17 +32,57 @@
 
 #include <atomic>
 
+using TimePoint = std::atomic<std::chrono::time_point<std::chrono::steady_clock>>;
+
+struct KeyspaceGCInfo
+{
+    DB::Timestamp ks_gc_sp;
+    TimePoint ks_gc_sp_update_time;
+
+    KeyspaceGCInfo()
+    {
+        ks_gc_sp_update_time = std::chrono::steady_clock::now();
+    }
+
+    KeyspaceGCInfo(const KeyspaceGCInfo & other)
+    {
+        ks_gc_sp = other.ks_gc_sp;
+        ks_gc_sp_update_time = std::chrono::steady_clock::now();
+    }
+
+    KeyspaceGCInfo & operator=(const KeyspaceGCInfo & other)
+    {
+        if (this != &other)
+        {
+            ks_gc_sp = other.ks_gc_sp;
+            ks_gc_sp_update_time = std::chrono::steady_clock::now();
+        }
+        return *this;
+    }
+};
+
 namespace DB
 {
 struct PDClientHelper
 {
     static constexpr int get_safepoint_maxtime = 120000; // 120s. waiting pd recover.
 
+    static bool enable_safepoint_v2;
+
     static Timestamp getGCSafePointWithRetry(
         const pingcap::pd::ClientPtr & pd_client,
+        KeyspaceID keyspace_id,
         bool ignore_cache = true,
         Int64 safe_point_update_interval_seconds = 30)
     {
+        // If keyspace id is `NullspaceID` it need to use safe point v1.
+        if (enable_safepoint_v2 && keyspace_id != NullspaceID)
+        {
+            auto gc_safe_point = getGCSafePointV2WithRetry(pd_client, keyspace_id, ignore_cache, safe_point_update_interval_seconds);
+            LOG_DEBUG(Logger::get(), "use safe point v2, keyspace_id={},gc_safe_point={}", keyspace_id, gc_safe_point);
+            return gc_safe_point;
+        }
+
         if (!ignore_cache)
         {
             // In case we cost too much to update safe point from PD.
@@ -59,6 +100,7 @@ struct PDClientHelper
             {
                 auto safe_point = pd_client->getGCSafePoint();
                 cached_gc_safe_point = safe_point;
+                LOG_DEBUG(Logger::get(), "use safe point v1, gc_safe_point={}", safe_point);
                 safe_point_last_update_time = std::chrono::steady_clock::now();
                 return safe_point;
             }
@@ -69,9 +111,71 @@ struct PDClientHelper
         }
     }
 
+    static Timestamp getGCSafePointV2WithRetry(
+        const pingcap::pd::ClientPtr & pd_client,
+        KeyspaceID keyspace_id,
+        bool ignore_cache = false,
+        Int64 safe_point_update_interval_seconds = 30)
+    {
+        if (!ignore_cache)
+        {
+            // In case we cost too much to update safe point from PD.
+            auto now = std::chrono::steady_clock::now();
+
+            auto ks_gc_info = get_ks_gc_sp(keyspace_id);
+            const auto duration = std::chrono::duration_cast<std::chrono::seconds>(now - ks_gc_info.ks_gc_sp_update_time.load());
+            const auto min_interval = std::max(Int64(1), safe_point_update_interval_seconds); // at least one second
+            if (duration.count() < min_interval)
+            {
+                return ks_gc_info.ks_gc_sp;
+            }
+        }
+
+        pingcap::kv::Backoffer bo(get_safepoint_maxtime);
+        for (;;)
+        {
+            try
+            {
+                auto ks_gc_sp = pd_client->getGCSafePointV2(keyspace_id);
+                update_ks_gc_sp_map(keyspace_id, ks_gc_sp);
+                return ks_gc_sp;
+            }
+            catch (pingcap::Exception & e)
+            {
+                bo.backoff(pingcap::kv::boPDRPC, e);
+            }
+        }
+    }
+
+    static void update_ks_gc_sp_map(KeyspaceID keyspace_id, Timestamp ks_gc_sp)
+    {
+        std::unique_lock<std::shared_mutex> lock(ks_gc_sp_mutex);
+        KeyspaceGCInfo newKeyspaceGCInfo;
+        newKeyspaceGCInfo.ks_gc_sp = ks_gc_sp;
+        newKeyspaceGCInfo.ks_gc_sp_update_time = std::chrono::steady_clock::now();
+        ks_gc_sp_map[keyspace_id] = newKeyspaceGCInfo;
+    }
+
+    static KeyspaceGCInfo get_ks_gc_sp(KeyspaceID keyspace_id)
+    {
+        std::shared_lock<std::shared_mutex> lock(ks_gc_sp_mutex);
+        return ks_gc_sp_map[keyspace_id];
+    }
+
+    static void remove_ks_gc_sp(KeyspaceID keyspace_id)
+    {
+        std::unique_lock<std::shared_mutex> lock(ks_gc_sp_mutex);
+        ks_gc_sp_map.erase(keyspace_id);
+    }
+
+
 private:
     static std::atomic<Timestamp> cached_gc_safe_point;
     static std::atomic<std::chrono::time_point<std::chrono::steady_clock>> safe_point_last_update_time;
+
+    // Keyspace gc safepoint cache and update time.
+    static std::unordered_map<KeyspaceID, KeyspaceGCInfo> ks_gc_sp_map;
+    static std::shared_mutex ks_gc_sp_mutex;
 };
 
 
diff --git a/dbms/src/Storages/Transaction/TiDB.cpp b/dbms/src/Storages/Transaction/TiDB.cpp
index fd39416a48a..c0fe1f4705b 100644
--- a/dbms/src/Storages/Transaction/TiDB.cpp
+++ b/dbms/src/Storages/Transaction/TiDB.cpp
@@ -1078,6 +1078,11 @@ ColumnID TableInfo::getColumnID(const String & name) const
         DB::ErrorCodes::LOGICAL_ERROR);
 }
 
+KeyspaceID TableInfo::getKeyspaceID() const
+{
+    return keyspace_id;
+}
+
 String TableInfo::getColumnName(const ColumnID id) const
 {
     for (const auto & col : columns)
diff --git a/dbms/src/Storages/Transaction/TiDB.h b/dbms/src/Storages/Transaction/TiDB.h
index ba4470958eb..01b5cfad7dd 100644
--- a/dbms/src/Storages/Transaction/TiDB.h
+++ b/dbms/src/Storages/Transaction/TiDB.h
@@ -399,6 +399,7 @@ struct TableInfo
 
     ColumnID getColumnID(const String & name) const;
     String getColumnName(ColumnID id) const;
+    KeyspaceID getKeyspaceID() const;
 
     const ColumnInfo & getColumnInfo(ColumnID id) const;
 
diff --git a/dbms/src/TiDB/Schema/SchemaSyncService.cpp b/dbms/src/TiDB/Schema/SchemaSyncService.cpp
index 4b70d733634..66a7a616210 100644
--- a/dbms/src/TiDB/Schema/SchemaSyncService.cpp
+++ b/dbms/src/TiDB/Schema/SchemaSyncService.cpp
@@ -77,7 +77,7 @@ void SchemaSyncService::addKeyspaceGCTasks()
                         /// They must be performed synchronously,
                         /// otherwise table may get mis-GC-ed if RECOVER was not properly synced caused by schema sync pause but GC runs too aggressively.
                         // GC safe point must be obtained ahead of syncing schema.
-                        auto gc_safe_point = PDClientHelper::getGCSafePointWithRetry(context.getTMTContext().getPDClient());
+                        auto gc_safe_point = PDClientHelper::getGCSafePointWithRetry(context.getTMTContext().getPDClient(), keyspace);
                         stage = "Sync schemas";
                         done_anything = syncSchemas(keyspace);
                         if (done_anything)
@@ -130,6 +130,7 @@ void SchemaSyncService::removeKeyspaceGCTasks()
         keyspace_handle_iter = keyspace_handle_map.erase(keyspace_handle_iter);
 
         context.getTMTContext().getSchemaSyncerManager()->removeSchemaSyncer(keyspace);
+        PDClientHelper::remove_ks_gc_sp(keyspace);
     }
 }