diff --git a/executor/point_get_test.go b/executor/point_get_test.go
index 405b5892d26e1..881ea0f53a4d8 100644
--- a/executor/point_get_test.go
+++ b/executor/point_get_test.go
@@ -208,6 +208,20 @@ func (s *testPointGetSuite) TestIssue25489(c *C) {
 	tk.MustExec("drop table if exists UK_RP16939;")
 }
 
+// issue #25320
+func (s *testPointGetSuite) TestDistinctPlan(c *C) {
+	tk := testkit.NewTestKit(c, s.store)
+	tk.MustExec("use test")
+	tk.MustExec("drop table if exists test_distinct;")
+	tk.MustExec(`CREATE TABLE test_distinct (
+		id bigint(18) NOT NULL COMMENT '主键',
+		b bigint(18) NOT NULL COMMENT '用户ID',
+		PRIMARY KEY (id)
+		) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_general_ci;`)
+	tk.MustExec("insert into test_distinct values (123456789101112131,223456789101112131),(123456789101112132,223456789101112131);")
+	tk.MustQuery("select distinct b from test_distinct where id in (123456789101112131,123456789101112132);").Check(testkit.Rows("223456789101112131"))
+}
+
 func (s *testPointGetSuite) TestPointGetCharPK(c *C) {
 	tk := testkit.NewTestKit(c, s.store)
 	tk.MustExec(`use test;`)
diff --git a/planner/core/point_get_plan.go b/planner/core/point_get_plan.go
index 1214b1b776cd2..6562894eae2db 100644
--- a/planner/core/point_get_plan.go
+++ b/planner/core/point_get_plan.go
@@ -713,7 +713,7 @@ func newBatchPointGetPlan(
 
 func tryWhereIn2BatchPointGet(ctx sessionctx.Context, selStmt *ast.SelectStmt) *BatchPointGetPlan {
 	if selStmt.OrderBy != nil || selStmt.GroupBy != nil ||
-		selStmt.Limit != nil || selStmt.Having != nil ||
+		selStmt.Limit != nil || selStmt.Having != nil || selStmt.Distinct ||
 		len(selStmt.WindowSpecs) > 0 {
 		return nil
 	}