diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/Dockerfile b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/Dockerfile
deleted file mode 100644
index a5b68c41c4..0000000000
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/Dockerfile
+++ /dev/null
@@ -1,10 +0,0 @@
-# Use an alpine image to make the runtime smaller
-FROM docker.io/python:3.12.7-alpine3.20
-RUN python -m pip install --upgrade pip
-
-COPY /requirements.txt /tmp/requirements.txt
-RUN pip install -r /tmp/requirements.txt
-
-COPY main.py /
-
-CMD [ "opentelemetry-instrument", "python", "main.py" ]
diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/README.rst b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/README.rst
index b079930d04..019e141c70 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/README.rst
+++ b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/README.rst
@@ -17,23 +17,7 @@ Minimally, update the `.env <.env>`_ file with your "OPENAI_API_KEY". An
 OTLP compatible endpoint should be listening for traces and logs on
 http://localhost:4318. If not, update "OTEL_EXPORTER_OTLP_ENDPOINT" as well.
 
-Run with Docker
----------------
-
-If you have Docker installed, you can run the example in one step:
-
-::
-
-    docker-compose run --build --rm python-opentelemetry-openai
-
-You should see a poem generated by OpenAI while traces and logs export to your
-configured observability tool.
-
-Run with Python
----------------
-
-If you prefer to run the example with Python, set up a virtual environment for
-the example like this:
+Next, set up a virtual environment like this:
 
 ::
 
@@ -42,7 +26,10 @@ the example like this:
     pip install "python-dotenv[cli]"
     pip install -r requirements.txt
 
-Now, run the example like this:
+Run
+---
+
+Run the example like this:
 
 ::
 
diff --git a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/docker-compose.yml b/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/docker-compose.yml
deleted file mode 100644
index 27e247e85d..0000000000
--- a/instrumentation-genai/opentelemetry-instrumentation-openai-v2/example/docker-compose.yml
+++ /dev/null
@@ -1,9 +0,0 @@
-services:
-  opentelemetry-python-openai:
-    container_name: opentelemetry-python-openai
-    build:
-      context: .
-    env_file:
-      - .env
-    environment:
-      OTEL_EXPORTER_OTLP_ENDPOINT: "http://host.docker.internal:4318"