diff --git a/instrumentation/opentelemetry-instrumentation-mysql/src/opentelemetry/instrumentation/mysql/__init__.py b/instrumentation/opentelemetry-instrumentation-mysql/src/opentelemetry/instrumentation/mysql/__init__.py
index d88dffde2b..18ef14dbd3 100644
--- a/instrumentation/opentelemetry-instrumentation-mysql/src/opentelemetry/instrumentation/mysql/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-mysql/src/opentelemetry/instrumentation/mysql/__init__.py
@@ -33,6 +33,12 @@
     cursor.execute("INSERT INTO test (testField) VALUES (123)")
     cursor.close()
     cnx.close()
+    
+    cnx = MySQLInstrumentor().instrument_connection(cnx)
+    cursor = cnx.cursor()
+    cursor.execute("INSERT INTO test (testField) VALUES (123)")
+    cursor.close()
+    cnx.close()
 
 API
 ---