diff --git a/doc/api/sqlite.md b/doc/api/sqlite.md
index 59202a1dc25c35..cfb3f48d70a42c 100644
--- a/doc/api/sqlite.md
+++ b/doc/api/sqlite.md
@@ -112,6 +112,10 @@ added: v22.5.0
     legacy database schemas. The enforcement of foreign key constraints can be
     enabled and disabled after opening the database using
     [`PRAGMA foreign_keys`][]. **Default:** `true`.
+  * `enableDoubleQuotedStringLiterals` {boolean} If `true`, SQLite will accept
+    [double-quoted string literals][]. This is not recommended but can be
+    enabled for compatibility with legacy database schemas.
+    **Default:** `false`.
 
 Constructs a new `DatabaseSync` instance.
 
@@ -332,6 +336,7 @@ exception.
 [`sqlite3_sql()`]: https://www.sqlite.org/c3ref/expanded_sql.html
 [connection]: https://www.sqlite.org/c3ref/sqlite3.html
 [data types]: https://www.sqlite.org/datatype3.html
+[double-quoted string literals]: https://www.sqlite.org/quirks.html#dblquote
 [in memory]: https://www.sqlite.org/inmemorydb.html
 [parameters are bound]: https://www.sqlite.org/c3ref/bind_blob.html
 [prepared statement]: https://www.sqlite.org/c3ref/stmt.html
diff --git a/src/node_sqlite.cc b/src/node_sqlite.cc
index 30c58d83f28a61..df6bb45ad60e7d 100644
--- a/src/node_sqlite.cc
+++ b/src/node_sqlite.cc
@@ -96,13 +96,15 @@ DatabaseSync::DatabaseSync(Environment* env,
                            Local<Object> object,
                            Local<String> location,
                            bool open,
-                           bool enable_foreign_keys_on_open)
+                           bool enable_foreign_keys_on_open,
+                           bool enable_dqs_on_open)
     : BaseObject(env, object) {
   MakeWeak();
   node::Utf8Value utf8_location(env->isolate(), location);
   location_ = utf8_location.ToString();
   connection_ = nullptr;
   enable_foreign_keys_on_open_ = enable_foreign_keys_on_open;
+  enable_dqs_on_open_ = enable_dqs_on_open;
 
   if (open) {
     Open();
@@ -132,6 +134,17 @@ bool DatabaseSync::Open() {
   int r = sqlite3_open_v2(location_.c_str(), &connection_, flags, nullptr);
   CHECK_ERROR_OR_THROW(env()->isolate(), connection_, r, SQLITE_OK, false);
 
+  r = sqlite3_db_config(connection_,
+                        SQLITE_DBCONFIG_DQS_DML,
+                        static_cast<int>(enable_dqs_on_open_),
+                        nullptr);
+  CHECK_ERROR_OR_THROW(env()->isolate(), connection_, r, SQLITE_OK, false);
+  r = sqlite3_db_config(connection_,
+                        SQLITE_DBCONFIG_DQS_DDL,
+                        static_cast<int>(enable_dqs_on_open_),
+                        nullptr);
+  CHECK_ERROR_OR_THROW(env()->isolate(), connection_, r, SQLITE_OK, false);
+
   int foreign_keys_enabled;
   r = sqlite3_db_config(connection_,
                         SQLITE_DBCONFIG_ENABLE_FKEY,
@@ -182,6 +195,7 @@ void DatabaseSync::New(const FunctionCallbackInfo<Value>& args) {
 
   bool open = true;
   bool enable_foreign_keys = true;
+  bool enable_dqs = false;
 
   if (args.Length() > 1) {
     if (!args[1]->IsObject()) {
@@ -222,10 +236,32 @@ void DatabaseSync::New(const FunctionCallbackInfo<Value>& args) {
       }
       enable_foreign_keys = enable_foreign_keys_v.As<Boolean>()->Value();
     }
+
+    Local<String> enable_dqs_string = FIXED_ONE_BYTE_STRING(
+        env->isolate(), "enableDoubleQuotedStringLiterals");
+    Local<Value> enable_dqs_v;
+    if (!options->Get(env->context(), enable_dqs_string)
+             .ToLocal(&enable_dqs_v)) {
+      return;
+    }
+    if (!enable_dqs_v->IsUndefined()) {
+      if (!enable_dqs_v->IsBoolean()) {
+        node::THROW_ERR_INVALID_ARG_TYPE(
+            env->isolate(),
+            "The \"options.enableDoubleQuotedStringLiterals\" argument must be "
+            "a boolean.");
+        return;
+      }
+      enable_dqs = enable_dqs_v.As<Boolean>()->Value();
+    }
   }
 
-  new DatabaseSync(
-      env, args.This(), args[0].As<String>(), open, enable_foreign_keys);
+  new DatabaseSync(env,
+                   args.This(),
+                   args[0].As<String>(),
+                   open,
+                   enable_foreign_keys,
+                   enable_dqs);
 }
 
 void DatabaseSync::Open(const FunctionCallbackInfo<Value>& args) {
diff --git a/src/node_sqlite.h b/src/node_sqlite.h
index 95203a353b21d2..40abf7b0d3edc3 100644
--- a/src/node_sqlite.h
+++ b/src/node_sqlite.h
@@ -22,7 +22,8 @@ class DatabaseSync : public BaseObject {
                v8::Local<v8::Object> object,
                v8::Local<v8::String> location,
                bool open,
-               bool enable_foreign_keys_on_open);
+               bool enable_foreign_keys_on_open,
+               bool enable_dqs_on_open);
   void MemoryInfo(MemoryTracker* tracker) const override;
   static void New(const v8::FunctionCallbackInfo<v8::Value>& args);
   static void Open(const v8::FunctionCallbackInfo<v8::Value>& args);
@@ -45,6 +46,7 @@ class DatabaseSync : public BaseObject {
   sqlite3* connection_;
   std::unordered_set<StatementSync*> statements_;
   bool enable_foreign_keys_on_open_;
+  bool enable_dqs_on_open_;
 };
 
 class StatementSync : public BaseObject {
diff --git a/test/parallel/test-sqlite-database-sync.js b/test/parallel/test-sqlite-database-sync.js
index 777b273e9a5aac..7979d01b568aa1 100644
--- a/test/parallel/test-sqlite-database-sync.js
+++ b/test/parallel/test-sqlite-database-sync.js
@@ -86,6 +86,34 @@ suite('DatabaseSync() constructor', () => {
     t.after(() => { db.close(); });
     db.exec('INSERT INTO bar (foo_id) VALUES (1)');
   });
+
+  test('throws if options.enableDoubleQuotedStringLiterals is provided but is not a boolean', (t) => {
+    t.assert.throws(() => {
+      new DatabaseSync('foo', { enableDoubleQuotedStringLiterals: 5 });
+    }, {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /The "options\.enableDoubleQuotedStringLiterals" argument must be a boolean/,
+    });
+  });
+
+  test('disables double-quoted string literals by default', (t) => {
+    const dbPath = nextDb();
+    const db = new DatabaseSync(dbPath);
+    t.after(() => { db.close(); });
+    t.assert.throws(() => {
+      db.exec('SELECT "foo";');
+    }, {
+      code: 'ERR_SQLITE_ERROR',
+      message: /no such column: "foo"/,
+    });
+  });
+
+  test('allows enabling double-quoted string literals', (t) => {
+    const dbPath = nextDb();
+    const db = new DatabaseSync(dbPath, { enableDoubleQuotedStringLiterals: true });
+    t.after(() => { db.close(); });
+    db.exec('SELECT "foo";');
+  });
 });
 
 suite('DatabaseSync.prototype.open()', () => {