diff --git a/src/bindgen/ir/constant.rs b/src/bindgen/ir/constant.rs
index 0013fce3..82087b78 100644
--- a/src/bindgen/ir/constant.rs
+++ b/src/bindgen/ir/constant.rs
@@ -841,12 +841,16 @@ impl Constant {
                 language_backend.write_literal(out, value);
             }
             Language::Cython => {
-                out.write("const ");
-                language_backend.write_type(out, &self.ty);
-                // For extern Cython declarations the initializer is ignored,
-                // but still useful as documentation, so we write it as a comment.
-                write!(out, " {} # = ", name);
-                language_backend.write_literal(out, value);
+                if matches!(self.value, Literal::PanicMacro(_)) {
+                    // Cython don't have a equivalent to `#error` directive
+                } else {
+                    out.write("const ");
+                    language_backend.write_type(out, &self.ty);
+                    // For extern Cython declarations the initializer is ignored,
+                    // but still useful as documentation, so we write it as a comment.
+                    write!(out, " {} # = ", name);
+                    language_backend.write_literal(out, value);
+                }
             }
         }