diff --git a/python/mlc_chat/compiler_pass/pipeline.py b/python/mlc_chat/compiler_pass/pipeline.py
index 81a79b0a21..83a69757ae 100644
--- a/python/mlc_chat/compiler_pass/pipeline.py
+++ b/python/mlc_chat/compiler_pass/pipeline.py
@@ -20,6 +20,7 @@
 from .fuse_ft_dequantize_matmul_epilogue import FuseFTDequantizeEpilogue
 from .fuse_transpose_matmul import FuseTransposeMatmul
 from .lift_global_buffer_alloc import LiftTIRGlobalBufferAlloc
+from .prune_relax_func import PruneRelaxFunc
 
 logger = logging.getLogger(__name__)
 
@@ -59,6 +60,7 @@ def transform_module(self, mod: IRModule, _ctx: tvm.transform.PassContext) -> IR
 
 @register_pipeline("mlc_llm")
 def _mlc_llm_pipeline(  # pylint: disable=too-many-arguments
+    flashinfer: bool = False,
     cublas_gemm: bool = False,
     variable_bounds: Dict[str, int] = None,
     additional_tirs: Dict[str, tvm.tir.PrimFunc] = None,
@@ -75,7 +77,8 @@ def _mlc_llm_pipeline(  # pylint: disable=too-many-arguments
     def _pipeline(mod: tvm.ir.IRModule, _ctx: tvm.transform.PassContext) -> tvm.ir.IRModule:
         seq = tvm.transform.Sequential(
             [
-                # Phase 0. Add additional information for compilation
+                # Phase 0. Add additional information for compilation and remove unused Relax func
+                PruneRelaxFunc(flashinfer=flashinfer),
                 AttachVariableBounds(variable_bounds),
                 AttachAdditionalPrimFuncs(additional_tirs),
                 _DebugDump("debug-phase0.py", debug_dump, show_meta=False),
diff --git a/python/mlc_chat/compiler_pass/prune_relax_func.py b/python/mlc_chat/compiler_pass/prune_relax_func.py
new file mode 100644
index 0000000000..5271140786
--- /dev/null
+++ b/python/mlc_chat/compiler_pass/prune_relax_func.py
@@ -0,0 +1,31 @@
+"""A pass that removes undesired Relax function from IRModule based on target."""
+import tvm
+from tvm import IRModule
+
+
+@tvm.transform.module_pass(opt_level=0, name="PruneRelaxFunc")
+class PruneRelaxFunc:  # pylint: disable=too-few-public-methods
+    """Removes undesired Relax function from IRModule based on target."""
+
+    def __init__(self, flashinfer: bool) -> None:
+        """Initializer.
+
+        Parameters
+        ----------
+        flashinfer : bool
+            A boolean indicating if flashinfer is enabled.
+        """
+        self.flashinfer = flashinfer
+
+    def transform_module(self, mod: IRModule, _ctx: tvm.transform.PassContext) -> IRModule:
+        """Entrypoint"""
+        func_dict = {}
+        for g_var, func in mod.functions_items():
+            # Remove "create_flashinfer_paged_kv_cache" for unsupported target
+            if g_var.name_hint == "create_flashinfer_paged_kv_cache" and not self.flashinfer:
+                continue
+            func_dict[g_var] = func
+        ret_mod = IRModule(func_dict)
+        if mod.attrs is not None:
+            ret_mod = ret_mod.with_attrs(mod.attrs)
+        return ret_mod
diff --git a/python/mlc_chat/interface/compile.py b/python/mlc_chat/interface/compile.py
index a483a055e7..9627a09ca2 100644
--- a/python/mlc_chat/interface/compile.py
+++ b/python/mlc_chat/interface/compile.py
@@ -166,6 +166,7 @@ def _find_kv_cache_bytes(model: nn.Module, model_config) -> int:
             args,
             pipeline=relax.get_pipeline(  # type: ignore
                 "mlc_llm",
+                flashinfer=args.opt.flashinfer,
                 cublas_gemm=args.opt.cublas_gemm,
                 variable_bounds=variable_bounds,
                 additional_tirs=additional_tirs,