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DESCRIPTION
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Package: ATACseqQCWorkshop
Title: Best practices for ATAC-seq QC and data analysis
Version: 0.1.0
Authors@R:
c(person(given = "Haibo",
family = "Liu",
role = c("aut", "cre"),
email = "[email protected]"),
person(given = "Jianhong",
family = "Ou",
role = c("aut"),
email = "[email protected]"),
person(given = "Kai",
family = "Hu",
role = c("aut"),
email = "[email protected]"),
person(given = "Lihua",
family = "Zhu",
role = c("aut"),
email = "[email protected]"))
Description: ATAC-seq, an assay for Transposase-Accessible Chromatin
using sequencing, is a rapid and sensitive method for chromatin
accessibility analysis. Compared to other methods, such as
MNase-seq, FAIRE-seq and DNAse-seq, ATAC-seq requires less
biological materials and time to process. In this workshop,
participants will not only gain the theoretical understanding of
the characteristics of ATAC-seq data and the workflow of ATAC-seq
data quality assessment, but will also obtain hands-on experience
in analyzing ATAC-seq data using the ATACseqQC package. We will
provide a brief introduction to the ATAC-seq technology, high
quality data generation and computational analysis workflow. Then,
we will give a demo to perform a comprehensive quality assessment
of a typical ATAC-seq dataset using the ATACseqQC package. Participants
will have the opportunity to analyze several excerpted datasets of
different quality. Detailed notes and R code will be provided for
reproducibility and follow-up practicing.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.0
Depends: R (>= 4.0), ATACseqQC, Biobase
Suggests: knitr, rmarkdown, pkgdown, BiocGenerics, S4Vectors, BSgenome, Biostrings,
ChIPpeakAnno, IRanges, GenomicRanges, GenomicAlignments, GenomeInfoDb,
GenomicScores, graphics, grid, limma, Rsamtools (>= 1.31.2), randomForest,
rtracklayer, stats, motifStack, preseqR, utils, KernSmooth, edgeR, BiocStyle,
BSgenome.Hsapiens.UCSC.hg38,TxDb.Hsapiens.UCSC.hg38.knownGene,
BSgenome.Hsapiens.UCSC.hg19, TxDb.Hsapiens.UCSC.hg19.knownGene,
MotifDb, trackViewer, SRAdb, png, jpeg
URL: https://haibol2016.github.io/ATACseqQCWorkshop/
BugReports: https://github.com/haibol2016/ATACseqQCWorkshop/issues/new/choose
VignetteBuilder: knitr
DockerImage: nemat1976/atacseqqcworkshop_2020:latest