diff --git a/src/webgpu/api/operation/resource_init/texture_zero.spec.ts b/src/webgpu/api/operation/resource_init/texture_zero.spec.ts
index 6e18fbfea82..91d8ddd16c2 100644
--- a/src/webgpu/api/operation/resource_init/texture_zero.spec.ts
+++ b/src/webgpu/api/operation/resource_init/texture_zero.spec.ts
@@ -9,7 +9,7 @@ TODO:
 
 import { makeTestGroup } from '../../../../common/framework/test_group.js';
 import { unreachable } from '../../../../common/util/util.js';
-import { kTextureFormatInfo } from '../../../format_info.js';
+import { isMultisampledTextureFormat, kTextureFormatInfo } from '../../../format_info.js';
 
 import { checkContentsByBufferCopy, checkContentsByTextureCopy } from './check_texture/by_copy.js';
 import {
@@ -47,6 +47,10 @@ g.test('uninitialized_texture_is_zero')
     t.selectDeviceOrSkipTestCase(kTextureFormatInfo[t.params.format].feature);
   })
   .fn(t => {
+    t.skipIf(
+      t.params.sampleCount > 1 && !isMultisampledTextureFormat(t.params.format, t.isCompatibility)
+    );
+
     const usage = getRequiredTextureUsage(
       t.params.format,
       t.params.sampleCount,
diff --git a/src/webgpu/api/validation/resource_usages/texture/in_pass_encoder.spec.ts b/src/webgpu/api/validation/resource_usages/texture/in_pass_encoder.spec.ts
index 34e1bd75ba7..49bc80ea6a1 100644
--- a/src/webgpu/api/validation/resource_usages/texture/in_pass_encoder.spec.ts
+++ b/src/webgpu/api/validation/resource_usages/texture/in_pass_encoder.spec.ts
@@ -10,6 +10,7 @@ import {
   kDepthStencilFormats,
   kDepthStencilFormatResolvedAspect,
   kTextureFormatInfo,
+  isMultisampledTextureFormat,
 } from '../../../../format_info.js';
 import { MaxLimitsTestMixin } from '../../../../gpu_test.js';
 import { ValidationTest } from '../../validation_test.js';
@@ -1156,6 +1157,7 @@ g.test('bindings_in_bundle')
 
     t.skipIfNeedStorageTexturesByResourceTypeAndNoStorageTextures(type0, GPUShaderStage.FRAGMENT);
     t.skipIfNeedStorageTexturesByResourceTypeAndNoStorageTextures(type1, GPUShaderStage.FRAGMENT);
+    t.skipIf(_sampleCount! > 1 && !isMultisampledTextureFormat('r32float', t.isCompatibility));
 
     // Two bindings are attached to the same texture view.
     const usage =