diff --git a/libcef/browser/browser_contents_delegate.cc b/libcef/browser/browser_contents_delegate.cc
index 08bdd0bda..c86c55ec4 100644
--- a/libcef/browser/browser_contents_delegate.cc
+++ b/libcef/browser/browser_contents_delegate.cc
@@ -105,6 +105,7 @@ void CefBrowserContentsDelegate::LoadingStateChanged(
 
   if (auto c = client()) {
     if (auto handler = c->GetLoadHandler()) {
+      auto navigation_lock = browser_info_->CreateNavigationLock();
       handler->OnLoadingStateChange(browser(), is_loading, can_go_back,
                                     can_go_forward);
     }
@@ -507,6 +508,7 @@ void CefBrowserContentsDelegate::OnLoadEnd(CefRefPtr<CefFrame> frame,
                                            int http_status_code) {
   if (auto c = client()) {
     if (auto handler = c->GetLoadHandler()) {
+      auto navigation_lock = browser_info_->CreateNavigationLock();
       handler->OnLoadEnd(browser(), frame, http_status_code);
     }
   }
@@ -565,6 +567,7 @@ void CefBrowserContentsDelegate::OnLoadStart(
     ui::PageTransition transition_type) {
   if (auto c = client()) {
     if (auto handler = c->GetLoadHandler()) {
+      auto navigation_lock = browser_info_->CreateNavigationLock();
       // On the handler that loading has started.
       handler->OnLoadStart(browser(), frame,
                            static_cast<cef_transition_type_t>(transition_type));
diff --git a/tests/ceftests/navigation_unittest.cc b/tests/ceftests/navigation_unittest.cc
index f4b1a368e..f0f98007d 100644
--- a/tests/ceftests/navigation_unittest.cc
+++ b/tests/ceftests/navigation_unittest.cc
@@ -1824,11 +1824,17 @@ class LoadNavTestHandler : public TestHandler {
     EXPECT_EQ(RT_MAIN_FRAME, request->GetResourceType());
     if (mode_ == LOAD || request->GetURL() == kLoadNav1) {
       EXPECT_EQ(kTransitionExplicitLoad, request->GetTransitionType());
-      EXPECT_FALSE(user_gesture);
+      if (IsChromeRuntimeEnabled()) {
+        // With the Chrome runtime this is true on initial navigation via
+        // chrome::AddTabAt() and also true for clicked links.
+        EXPECT_TRUE(user_gesture);
+      } else {
+        EXPECT_FALSE(user_gesture);
+      }
     } else {
       EXPECT_EQ(ExpectedOpenURLTransitionType(), request->GetTransitionType());
 
-      if (mode_ == LEFT_CLICK) {
+      if (mode_ == LEFT_CLICK || IsChromeRuntimeEnabled()) {
         EXPECT_TRUE(user_gesture);
       } else {
         EXPECT_FALSE(user_gesture);
diff --git a/tests/ceftests/resource_request_handler_unittest.cc b/tests/ceftests/resource_request_handler_unittest.cc
index cec388389..be5fe50b7 100644
--- a/tests/ceftests/resource_request_handler_unittest.cc
+++ b/tests/ceftests/resource_request_handler_unittest.cc
@@ -528,7 +528,13 @@ class BasicResponseTest : public TestHandler {
     }
     EXPECT_TRUE(frame->IsMain());
 
-    EXPECT_FALSE(user_gesture);
+    if (IsChromeRuntimeEnabled()) {
+      // With the Chrome runtime this is true on initial navigation via
+      // chrome::AddTabAt() and also true for clicked links.
+      EXPECT_TRUE(user_gesture);
+    } else {
+      EXPECT_FALSE(user_gesture);
+    }
     if (on_before_browse_ct_ == 0 || mode_ == RESTART_RESOURCE_RESPONSE) {
       EXPECT_FALSE(is_redirect) << on_before_browse_ct_;
     } else {
@@ -957,7 +963,13 @@ class BasicResponseTest : public TestHandler {
     EXPECT_EQ(resource_handler_created_ct_, resource_handler_destroyed_ct_);
 
     if (IsAborted()) {
-      EXPECT_EQ(0, on_resource_load_complete_ct_);
+      if (IsChromeRuntimeEnabled()) {
+        // Using the Chrome runtime OnResourceLoadComplete may be called with
+        // UR_FAILED.
+        EXPECT_NEAR(0, on_resource_load_complete_ct_, 1);
+      } else {
+        EXPECT_EQ(0, on_resource_load_complete_ct_);
+      }
     } else {
       EXPECT_EQ(1, on_resource_load_complete_ct_);
     }
@@ -1520,16 +1532,24 @@ class SubresourceResponseTest : public RoutingTestHandler {
       EXPECT_EQ(browser_id_, browser->GetIdentifier());
     }
 
-    if (IsMainURL(request->GetURL())) {
+    const std::string& url = request->GetURL();
+    if (IsMainURL(url)) {
       EXPECT_TRUE(frame->IsMain());
-    } else if (IsSubURL(request->GetURL())) {
+    } else if (IsSubURL(url)) {
       EXPECT_FALSE(frame->IsMain());
       EXPECT_TRUE(subframe_);
     } else {
       EXPECT_FALSE(true);  // Not reached.
     }
 
-    EXPECT_FALSE(user_gesture);
+    if (IsChromeRuntimeEnabled() && IsMainURL(url)) {
+      // With the Chrome runtime this is true on initial navigation via
+      // chrome::AddTabAt() and also true for clicked links.
+      EXPECT_TRUE(user_gesture);
+    } else {
+      EXPECT_FALSE(user_gesture);
+    }
+
     EXPECT_FALSE(is_redirect);
 
     on_before_browse_ct_++;