diff --git a/x-pack/plugins/security_solution/public/management/cypress/e2e/mocked_data/isolate.cy.ts b/x-pack/plugins/security_solution/public/management/cypress/e2e/mocked_data/isolate.cy.ts
index 118eadd4fcd5b..6894d7ac9dd29 100644
--- a/x-pack/plugins/security_solution/public/management/cypress/e2e/mocked_data/isolate.cy.ts
+++ b/x-pack/plugins/security_solution/public/management/cypress/e2e/mocked_data/isolate.cy.ts
@@ -189,7 +189,8 @@ describe('Isolate command', () => {
     });
   });
 
-  describe('from Cases', () => {
+  // Flaky: https://github.com/elastic/security-team/issues/7048
+  describe.skip('from Cases', () => {
     let endpointData: ReturnTypeFromChainable<typeof indexEndpointHosts> | undefined;
     let caseData: ReturnTypeFromChainable<typeof indexNewCase> | undefined;
     let alertData: ReturnTypeFromChainable<typeof indexEndpointRuleAlerts> | undefined;
diff --git a/x-pack/plugins/security_solution/public/management/cypress/e2e/mocked_data/responder.cy.ts b/x-pack/plugins/security_solution/public/management/cypress/e2e/mocked_data/responder.cy.ts
index 881d1ec449eec..47cf9cc30d204 100644
--- a/x-pack/plugins/security_solution/public/management/cypress/e2e/mocked_data/responder.cy.ts
+++ b/x-pack/plugins/security_solution/public/management/cypress/e2e/mocked_data/responder.cy.ts
@@ -38,7 +38,8 @@ describe('When accessing Endpoint Response Console', () => {
     login();
   });
 
-  describe('from Cases', () => {
+  // Flaky: https://github.com/elastic/security-team/issues/7048
+  describe.skip('from Cases', () => {
     let endpointData: ReturnTypeFromChainable<typeof indexEndpointHosts>;
     let caseData: ReturnTypeFromChainable<typeof indexNewCase>;
     let alertData: ReturnTypeFromChainable<typeof indexEndpointRuleAlerts>;