index.html

<!DOCTYPE html>
<html lang="en">
  <head>
    <title>Nice meme!</title>
    <style type="text/css">
      html {
        font-family: sans-serif;
        -ms-text-size-adjust: 100%;
        -webkit-text-size-adjust: 100%;
      }
      body {
        margin: 0;
      }
      h1 {
        font-size: 5em;
        margin: 0.67em 0;
        text-align: center;
      }
      audio:not([controls]) {
        display: none;
        height: 0;
      }
    </style>
  </head>
  <body>
    <h1>Nice meme!</h1>
    <audio id="audio" src="nicememe.mp3" type="audio/mpeg" preload="auto" autoplay>
    <script type="text/javascript">
      // autoplay is disabled on mobile web
      document.addEventListener('touchend', function handleTouch () {
        document.getElementById('audio').play();
      });
    </script>
  </body>
</html>