diff --git a/src/libraries/System.Runtime/tests/System.Runtime.Tests/System/ArrayTests.cs b/src/libraries/System.Runtime/tests/System.Runtime.Tests/System/ArrayTests.cs
index 998094377be4f4..ccaba707130386 100644
--- a/src/libraries/System.Runtime/tests/System.Runtime.Tests/System/ArrayTests.cs
+++ b/src/libraries/System.Runtime/tests/System.Runtime.Tests/System/ArrayTests.cs
@@ -1599,7 +1599,6 @@ public static void Copy_SourceAndDestinationNeverConvertible_ThrowsArrayTypeMism
         }
 
         [Fact]
-        [SkipOnMono("https://github.com/dotnet/runtime/issues/104197")]
         public static unsafe void Copy_CompatiblePointers()
         {
             // Can copy between compatible pointers
diff --git a/src/mono/mono/metadata/class.c b/src/mono/mono/metadata/class.c
index 043338c14899d9..2117c94c06a840 100644
--- a/src/mono/mono/metadata/class.c
+++ b/src/mono/mono/metadata/class.c
@@ -3582,6 +3582,7 @@ mono_class_is_subclass_of_internal (MonoClass *klass, MonoClass *klassc,
 				    gboolean check_interfaces)
 {
 	MONO_REQ_GC_UNSAFE_MODE;
+
 	/* FIXME test for interfaces with variant generic arguments */
 	if (check_interfaces) {
 		mono_class_init_internal (klass);
@@ -4284,13 +4285,9 @@ mono_class_is_assignable_from_general (MonoClass *klass, MonoClass *oklass, gboo
 
 		MonoClass *eclass;
 		MonoClass *eoclass;
-		if (signature_assignment) {
-			eclass = composite_type_to_reduced_element_type (klass);
-			eoclass = composite_type_to_reduced_element_type (oklass);
-		} else {
-			eclass = m_class_get_cast_class (klass);
-			eoclass = m_class_get_cast_class (oklass);
-		}
+
+		eclass = composite_type_to_reduced_element_type (klass);
+		eoclass = composite_type_to_reduced_element_type (oklass);
 
 		*result = (eclass == eoclass);
 		return;
diff --git a/src/mono/mono/metadata/icall.c b/src/mono/mono/metadata/icall.c
index 67cd6470df19db..43f3d32653f321 100644
--- a/src/mono/mono/metadata/icall.c
+++ b/src/mono/mono/metadata/icall.c
@@ -199,12 +199,7 @@ ves_icall_System_Array_GetValueImpl (MonoObjectHandleOnStack array_handle, MonoO
 	MonoClass * const array_class = mono_object_class (array);
 	MonoClass * const element_class = m_class_get_element_class (array_class);
 
-	if (m_class_is_native_pointer (element_class)) {
-		mono_error_set_not_supported (error, NULL);
-		return;
-	}
-
-	if (m_class_is_valuetype (element_class)) {
+	if (m_class_is_valuetype (element_class) || mono_class_is_pointer (element_class)) {
 		gsize element_size = mono_array_element_size (array_class);
 		gpointer element_address = mono_array_addr_with_size_fast (array, element_size, (gsize)pos);
 		MonoObject *res = mono_value_box_checked (element_class, element_address, error);
@@ -872,13 +867,16 @@ ves_icall_System_Array_FastCopy (MonoObjectHandleOnStack source_handle, int sour
 		if (m_class_is_valuetype (dest_class) || m_class_is_enumtype (dest_class) ||
 		 	m_class_is_valuetype (src_class) || m_class_is_valuetype (src_class))
 			return FALSE;
-
-		/* It's only safe to copy between arrays if we can ensure the source will always have a subtype of the destination. We bail otherwise. */
-		if (!mono_class_is_subclass_of_internal (src_class, dest_class, FALSE))
-			return FALSE;
-
-		if (m_class_is_native_pointer (src_class) || m_class_is_native_pointer (dest_class))
-			return FALSE;
+		
+		if (mono_class_is_pointer (dest_class) || mono_class_is_pointer (src_class)) {
+			/* if we're copying between at least one array of pointers, only allow it if both dest_class is assignable from src_class (checked above, and src_class is assignable from dest_class).  This should only be true if both src_class and dest_class have a common cast_class. (for example: int*[] and uint*[] are ok, but void*[] and int*[] are not)). */
+			if (!mono_class_is_assignable_from_internal (dest_class, src_class))
+				return FALSE;
+		} else {
+			/* It's only safe to copy between arrays if we can ensure the source will always have a subtype of the destination. We bail otherwise. */
+			if (!mono_class_is_subclass_of_internal (src_class, dest_class, FALSE))
+				return FALSE;
+		}
 	}
 
 	if (m_class_is_valuetype (dest_class)) {
diff --git a/src/mono/mono/metadata/object.c b/src/mono/mono/metadata/object.c
index 2a0e9e9834e094..1c1a632a4003e7 100644
--- a/src/mono/mono/metadata/object.c
+++ b/src/mono/mono/metadata/object.c
@@ -6529,7 +6529,7 @@ mono_value_box_handle (MonoClass *klass, gpointer value, MonoError *error)
 
 	error_init (error);
 
-	g_assert (m_class_is_valuetype (klass));
+	g_assert (m_class_is_valuetype (klass) || mono_class_is_pointer (klass));
 	g_assert (value != NULL);
 	if (G_UNLIKELY (m_class_is_byreflike (klass))) {
 		char *full_name = mono_type_get_full_name (klass);