diff --git a/src/purify.ts b/src/purify.ts
index 631b70cd..458a8e92 100644
--- a/src/purify.ts
+++ b/src/purify.ts
@@ -125,7 +125,8 @@ function createDOMPurify(window: WindowLike = getGlobal()): DOMPurify {
   if (
     !window ||
     !window.document ||
-    window.document.nodeType !== NODE_TYPE.document
+    window.document.nodeType !== NODE_TYPE.document ||
+    !window.Element
   ) {
     // Not running in a browser, provide a factory function
     // so that you can pass your own Window
diff --git a/test/test-suite.js b/test/test-suite.js
index 17329d5c..4317f143 100644
--- a/test/test-suite.js
+++ b/test/test-suite.js
@@ -870,6 +870,18 @@
         DOMPurify({ document: 'not really a document' }).sanitize,
         undefined
       );
+      assert.strictEqual(
+        typeof DOMPurify({ ...window, Element: undefined }).version,
+        'string'
+      );
+      assert.strictEqual(
+        DOMPurify({ ...window, Element: undefined }).isSupported,
+        false
+      );
+      assert.strictEqual(
+        DOMPurify({ ...window, Element: undefined }).sanitize,
+        undefined
+      );
       assert.strictEqual(typeof DOMPurify(window).version, 'string');
       assert.strictEqual(typeof DOMPurify(window).sanitize, 'function');
     });