diff --git a/CHANGELOG.md b/CHANGELOG.md
index 3eb2b2f65be..9014fa2b95d 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -44,6 +44,8 @@ Ref: https://keepachangelog.com/en/1.0.0/
 
 ### Improvements
 
+* (apps/27-interchain-accounts) [\#6436](https://github.com/cosmos/ibc-go/pull/6436) Refactor ICA host keeper instantiation method to avoid panic related to proto files.
+
 ### Features
 
 ### Bug Fixes
diff --git a/modules/apps/27-interchain-accounts/host/keeper/keeper.go b/modules/apps/27-interchain-accounts/host/keeper/keeper.go
index 06fd63ba5cd..900ea4069a7 100644
--- a/modules/apps/27-interchain-accounts/host/keeper/keeper.go
+++ b/modules/apps/27-interchain-accounts/host/keeper/keeper.go
@@ -7,6 +7,7 @@ import (
 
 	gogoproto "github.com/cosmos/gogoproto/proto"
 	"google.golang.org/protobuf/proto"
+	"google.golang.org/protobuf/reflect/protodesc"
 	"google.golang.org/protobuf/reflect/protoreflect"
 
 	msgv1 "cosmossdk.io/api/cosmos/msg/v1"
@@ -252,7 +253,15 @@ func (k Keeper) SetInterchainAccountAddress(ctx sdk.Context, connectionID, portI
 
 // newModuleQuerySafeAllowList returns a list of all query paths labeled with module_query_safe in the proto files.
 func newModuleQuerySafeAllowList() []string {
-	protoFiles, err := gogoproto.MergedRegistry()
+	fds, err := gogoproto.MergedGlobalFileDescriptors()
+	if err != nil {
+		panic(err)
+	}
+	// create the files using 'AllowUnresolvable' to avoid
+	// unnecessary panic: https://github.com/cosmos/ibc-go/issues/6435
+	protoFiles, err := protodesc.FileOptions{
+		AllowUnresolvable: true,
+	}.NewFiles(fds)
 	if err != nil {
 		panic(err)
 	}