diff --git a/.changeset/many-seas-listen.md b/.changeset/many-seas-listen.md
new file mode 100644
index 000000000..e34c97ce3
--- /dev/null
+++ b/.changeset/many-seas-listen.md
@@ -0,0 +1,5 @@
+---
+"aws-sdk-js-codemod": patch
+---
+
+Use value from service param for creating DynamoDB DocumentClient
diff --git a/src/transforms/v2-to-v3/__fixtures__/ddb-doc-client/param-service.input.js b/src/transforms/v2-to-v3/__fixtures__/ddb-doc-client/param-service.input.js
new file mode 100644
index 000000000..1e9d6d3a6
--- /dev/null
+++ b/src/transforms/v2-to-v3/__fixtures__/ddb-doc-client/param-service.input.js
@@ -0,0 +1,6 @@
+import AWS from "aws-sdk";
+
+const params = { region: "us-west-2" };
+const documentClient = new AWS.DynamoDB.DocumentClient({
+  service: new AWS.DynamoDB(params),
+});
\ No newline at end of file
diff --git a/src/transforms/v2-to-v3/__fixtures__/ddb-doc-client/param-service.output.js b/src/transforms/v2-to-v3/__fixtures__/ddb-doc-client/param-service.output.js
new file mode 100644
index 000000000..25d87b415
--- /dev/null
+++ b/src/transforms/v2-to-v3/__fixtures__/ddb-doc-client/param-service.output.js
@@ -0,0 +1,5 @@
+import { DynamoDBDocument } from "@aws-sdk/lib-dynamodb";
+import { DynamoDB } from "@aws-sdk/client-dynamodb";
+
+const params = { region: "us-west-2" };
+const documentClient = DynamoDBDocument.from(new DynamoDB(params));
\ No newline at end of file
diff --git a/src/transforms/v2-to-v3/client-instances/getDynamoDBForDocClient.ts b/src/transforms/v2-to-v3/client-instances/getDynamoDBForDocClient.ts
new file mode 100644
index 000000000..235e7b504
--- /dev/null
+++ b/src/transforms/v2-to-v3/client-instances/getDynamoDBForDocClient.ts
@@ -0,0 +1,43 @@
+import { ASTPath, JSCodeshift, NewExpression, ObjectProperty, Property } from "jscodeshift";
+
+import { DYNAMODB, OBJECT_PROPERTY_TYPE_LIST } from "../config";
+
+export interface GetDynamoDBForDocClientOptions {
+  v2ClientLocalName?: string;
+}
+
+export const getDynamoDBForDocClient = (
+  j: JSCodeshift,
+  v2DocClientNewExpression: ASTPath<NewExpression>,
+  { v2ClientLocalName }: GetDynamoDBForDocClientOptions
+) => {
+  // Return value in `service` param if it's provided.
+  if (v2DocClientNewExpression.node.arguments.length > 0) {
+    const params = v2DocClientNewExpression.node.arguments[0];
+    if (params.type === "ObjectExpression") {
+      const serviceProperty = params.properties.find((property) => {
+        if (!OBJECT_PROPERTY_TYPE_LIST.includes(property.type)) {
+          return false;
+        }
+        const propertyKey = (property as Property | ObjectProperty).key;
+        if (propertyKey.type !== "Identifier") {
+          return false;
+        }
+        if (propertyKey.name === "service") {
+          return true;
+        }
+      }) as Property | ObjectProperty | undefined;
+
+      if (serviceProperty) {
+        // The value here will work in most Document Client creations.
+        // Adding typecast to skip TypeScript errors.
+        return serviceProperty.value as NewExpression;
+      }
+    }
+  }
+
+  return j.newExpression(
+    v2ClientLocalName ? j.identifier(v2ClientLocalName) : j.identifier(DYNAMODB),
+    v2DocClientNewExpression.node.arguments
+  );
+};
diff --git a/src/transforms/v2-to-v3/client-instances/replaceDocClientCreation.ts b/src/transforms/v2-to-v3/client-instances/replaceDocClientCreation.ts
index 3ac766673..80d5f1cfd 100644
--- a/src/transforms/v2-to-v3/client-instances/replaceDocClientCreation.ts
+++ b/src/transforms/v2-to-v3/client-instances/replaceDocClientCreation.ts
@@ -1,7 +1,7 @@
 import { Collection, JSCodeshift } from "jscodeshift";
 
-import { DYNAMODB } from "../config";
 import { getDocClientNewExpression } from "../utils";
+import { getDynamoDBForDocClient } from "./getDynamoDBForDocClient";
 
 export interface ReplaceDocClientCreationOptions {
   v2ClientLocalName: string;
@@ -19,7 +19,7 @@ export const replaceDocClientCreation = (
       .replaceWith((v2DocClientNewExpression) =>
         j.callExpression(
           j.memberExpression(j.identifier("DynamoDBDocument"), j.identifier("from")),
-          [j.newExpression(j.identifier(DYNAMODB), v2DocClientNewExpression.node.arguments)]
+          [getDynamoDBForDocClient(j, v2DocClientNewExpression, { v2ClientLocalName })]
         )
       );
   }
@@ -28,7 +28,7 @@ export const replaceDocClientCreation = (
     .find(j.NewExpression, getDocClientNewExpression({ v2ClientLocalName }))
     .replaceWith((v2DocClientNewExpression) =>
       j.callExpression(j.memberExpression(j.identifier("DynamoDBDocument"), j.identifier("from")), [
-        j.newExpression(j.identifier(v2ClientLocalName), v2DocClientNewExpression.node.arguments),
+        getDynamoDBForDocClient(j, v2DocClientNewExpression, { v2ClientLocalName }),
       ])
     );
 };