diff --git a/requirements.bazel.txt b/requirements.bazel.txt
index 2ef85776d14b6..f544de0025d4b 100644
--- a/requirements.bazel.txt
+++ b/requirements.bazel.txt
@@ -28,7 +28,6 @@ pyasn1==0.5.0
 rsa==4.9
 greenlet==1.1.3.post0
 zope.interface==6.1
-opentelemetry-sdk==1.21.0
 opentelemetry-api==1.21.0
 importlib-metadata==7.0.1
 Deprecated==1.2.14
diff --git a/src/python/grpcio_observability/README.rst b/src/python/grpcio_observability/README.rst
index a597057198f52..a4122f79bd88f 100644
--- a/src/python/grpcio_observability/README.rst
+++ b/src/python/grpcio_observability/README.rst
@@ -62,7 +62,6 @@ gRPC Python Observability Depends on the following packages:
 ::
 
   grpcio
-  opentelemetry-sdk==1.21.0
   opentelemetry-api==1.21.0
 
 
diff --git a/src/python/grpcio_observability/grpc_observability/BUILD.bazel b/src/python/grpcio_observability/grpc_observability/BUILD.bazel
index afb35e43c3f66..6939cbbd57baa 100644
--- a/src/python/grpcio_observability/grpc_observability/BUILD.bazel
+++ b/src/python/grpcio_observability/grpc_observability/BUILD.bazel
@@ -53,7 +53,7 @@ pyx_library(
     ],
 )
 
-# Since `opentelemetry-sdk` and `opentelemetry-api` are non-hermetic,
+# Since `opentelemetry-api` is non-hermetic,
 # pyobservability is for internal use only.
 py_library(
     name = "_opentelemetry_observability",
@@ -64,7 +64,6 @@ py_library(
         "_open_telemetry_plugin.py",
     ],
     deps = [
-        requirement("opentelemetry-sdk"),
         requirement("opentelemetry-api"),
     ],
 )
diff --git a/src/python/grpcio_observability/setup.py b/src/python/grpcio_observability/setup.py
index cac2417d91934..4d4ebbeec57fa 100644
--- a/src/python/grpcio_observability/setup.py
+++ b/src/python/grpcio_observability/setup.py
@@ -290,7 +290,6 @@ def extension_modules():
     install_requires=[
         "grpcio=={version}".format(version=grpc_version.VERSION),
         "setuptools>=59.6.0",
-        "opentelemetry-sdk==1.21.0",
         "opentelemetry-api==1.21.0",
     ],
     cmdclass={