diff --git a/test/e2e/specs/editor/various/pattern-overrides.spec.js b/test/e2e/specs/editor/various/pattern-overrides.spec.js
new file mode 100644
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+++ b/test/e2e/specs/editor/various/pattern-overrides.spec.js
@@ -0,0 +1,219 @@
+/**
+ * WordPress dependencies
+ */
+const { test, expect } = require( '@wordpress/e2e-test-utils-playwright' );
+
+test.describe( 'Pattern Overrides', () => {
+	test.beforeAll( async ( { requestUtils } ) => {
+		await Promise.all( [
+			requestUtils.activateTheme( 'emptytheme' ),
+			requestUtils.setGutenbergExperiments( [
+				'gutenberg-pattern-partial-syncing',
+			] ),
+			requestUtils.deleteAllBlocks(),
+		] );
+	} );
+
+	test.afterEach( async ( { requestUtils } ) => {
+		await requestUtils.deleteAllBlocks();
+	} );
+
+	test.afterAll( async ( { requestUtils } ) => {
+		await Promise.all( [
+			requestUtils.setGutenbergExperiments( [] ),
+			requestUtils.activateTheme( 'twentytwentyone' ),
+		] );
+	} );
+
+	test( 'Create a pattern with overrides', async ( {
+		page,
+		admin,
+		editor,
+	} ) => {
+		let patternId;
+		let editableParagraphId;
+
+		await test.step( 'Create a synced pattern and assign blocks to allow overrides', async () => {
+			await admin.visitSiteEditor( { path: '/patterns' } );
+
+			await page
+				.getByRole( 'region', { name: 'Navigation' } )
+				.getByRole( 'button', { name: 'Create pattern' } )
+				.click();
+
+			await page
+				.getByRole( 'menu', { name: 'Create pattern' } )
+				.getByRole( 'menuitem', { name: 'Create pattern' } )
+				.click();
+
+			const createPatternDialog = page.getByRole( 'dialog', {
+				name: 'Create pattern',
+			} );
+			await createPatternDialog
+				.getByRole( 'textbox', { name: 'Name' } )
+				.fill( 'Pattern with overrides' );
+			await createPatternDialog
+				.getByRole( 'checkbox', { name: 'Synced' } )
+				.setChecked( true );
+			await createPatternDialog
+				.getByRole( 'button', { name: 'Create' } )
+				.click();
+
+			await editor.canvas
+				.getByRole( 'button', { name: 'Add default block' } )
+				.click();
+			await page.keyboard.type( 'This paragraph can be edited' );
+			await page.keyboard.press( 'Enter' );
+			await page.keyboard.type( "This one can't" );
+
+			await editor.canvas
+				.getByRole( 'document', { name: 'Block: Paragraph' } )
+				.filter( { hasText: 'This paragraph can be edited' } )
+				.focus();
+			await editor.openDocumentSettingsSidebar();
+			const editorSettings = page.getByRole( 'region', {
+				name: 'Editor settings',
+			} );
+			const advancedPanel = editorSettings.getByRole( 'button', {
+				name: 'Advanced',
+			} );
+			if (
+				( await advancedPanel.getAttribute( 'aria-expanded' ) ) ===
+				'false'
+			) {
+				await advancedPanel.click();
+			}
+			await editorSettings
+				.getByRole( 'checkbox', { name: 'Allow instance overrides' } )
+				.setChecked( true );
+
+			await expect.poll( editor.getBlocks ).toMatchObject( [
+				{
+					name: 'core/paragraph',
+					attributes: {
+						content: 'This paragraph can be edited',
+						metadata: {
+							id: expect.any( String ),
+							bindings: {
+								content: {
+									source: { name: 'pattern_attributes' },
+								},
+							},
+						},
+					},
+				},
+				{
+					name: 'core/paragraph',
+					attributes: { content: "This one can't" },
+				},
+			] );
+
+			await page
+				.getByRole( 'region', { name: 'Editor top bar' } )
+				.getByRole( 'button', { name: 'Save' } )
+				.click();
+			await page
+				.getByRole( 'region', { name: 'Save panel' } )
+				.getByRole( 'button', { name: 'Save' } )
+				.click();
+
+			await expect(
+				page.getByRole( 'button', { name: 'Dismiss this notice' } )
+			).toBeVisible();
+
+			patternId = new URL( page.url() ).searchParams.get( 'postId' );
+			const blocks = await editor.getBlocks();
+			editableParagraphId = blocks[ 0 ].attributes.metadata.id;
+		} );
+
+		await test.step( 'Create a post and insert the pattern with overrides', async () => {
+			await admin.createNewPost();
+
+			await editor.insertBlock( {
+				name: 'core/block',
+				attributes: { ref: patternId },
+			} );
+			await editor.insertBlock( {
+				name: 'core/block',
+				attributes: { ref: patternId },
+			} );
+
+			const patternBlocks = editor.canvas.getByRole( 'document', {
+				name: 'Block: Pattern',
+			} );
+			const paragraphs = patternBlocks.first().getByRole( 'document', {
+				name: 'Block: Paragraph',
+			} );
+			await expect( paragraphs.first() ).not.toHaveAttribute(
+				'inert',
+				'true'
+			);
+			await expect( paragraphs.last() ).toHaveAttribute(
+				'inert',
+				'true'
+			);
+
+			await expect( paragraphs.first() ).toHaveText(
+				'This paragraph can be edited'
+			);
+
+			await paragraphs.first().selectText();
+			await page.keyboard.type( 'I would word it this way' );
+
+			await patternBlocks
+				.last()
+				.getByRole( 'document', {
+					name: 'Block: Paragraph',
+				} )
+				.first()
+				.selectText();
+			await page.keyboard.type( 'This one is different' );
+
+			await expect.poll( editor.getBlocks ).toMatchObject( [
+				{
+					name: 'core/block',
+					attributes: {
+						ref: patternId,
+						overrides: {
+							[ editableParagraphId ]: {
+								content: 'I would word it this way',
+							},
+						},
+					},
+				},
+				{
+					name: 'core/block',
+					attributes: {
+						ref: patternId,
+						overrides: {
+							[ editableParagraphId ]: {
+								content: 'This one is different',
+							},
+						},
+					},
+				},
+			] );
+
+			await page
+				.getByRole( 'region', { name: 'Editor top bar' } )
+				.getByRole( 'button', { name: 'Publish' } )
+				.click();
+			const editorPublishPanel = page.getByRole( 'region', {
+				name: 'Editor publish',
+			} );
+			await editorPublishPanel
+				.getByRole( 'button', { name: 'Publish', exact: true } )
+				.click();
+			await editorPublishPanel
+				.getByRole( 'link', { name: 'View post' } )
+				.click();
+
+			await expect( page.locator( 'p' ) ).toContainText( [
+				'I would word it this way',
+				'This one can’t',
+				'This one is different',
+				'This one can’t',
+			] );
+		} );
+	} );
+} );