diff --git a/CHANGELOG.md b/CHANGELOG.md
index 43619bd19c4..4db5b4fdc57 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -24,6 +24,7 @@ and this project adheres to [Semantic Versioning](http://semver.org/spec/v2.0.0.
 - Remove FFI definition `PyFrame_ClearFreeList` when building for Python 3.9. [#1341](https://github.com/PyO3/pyo3/pull/1341)
 - Remove FFI definition `_PyDict_Contains` when building for Python 3.10. [#1341](https://github.com/PyO3/pyo3/pull/1341)
 - Remove FFI definitions `PyGen_NeedsFinalizing`, `PyImport_Cleanup` (for 3.9 and up), and `PyOS_InitInterrupts` (3.10). [#1348](https://github.com/PyO3/pyo3/pull/1348)
+- Remove FFI definitions for `PyUnicode_FromUnicode`, `PyUnicode_AsUnicode` and `PyUnicode_AsUnicodeAndSize`, which will be removed due to [PEP 613](https://www.python.org/dev/peps/pep-0623/).
 
 ### Fixed
 - Stop including `Py_TRACE_REFS` config setting automatically if `Py_DEBUG` is set on Python 3.8 and up. [#1334](https://github.com/PyO3/pyo3/pull/1334)
diff --git a/src/ffi/unicodeobject.rs b/src/ffi/unicodeobject.rs
index 0ecfbac9e6f..9e8f5eac72e 100644
--- a/src/ffi/unicodeobject.rs
+++ b/src/ffi/unicodeobject.rs
@@ -58,9 +58,6 @@ extern "C" {
         length: Py_ssize_t,
         fill_char: Py_UCS4,
     ) -> Py_ssize_t;
-    #[cfg(not(Py_LIMITED_API))]
-    #[cfg_attr(PyPy, link_name = "PyPyUnicode_FromUnicode")]
-    pub fn PyUnicode_FromUnicode(u: *const Py_UNICODE, size: Py_ssize_t) -> *mut PyObject;
 
     #[cfg_attr(PyPy, link_name = "PyPyUnicode_FromStringAndSize")]
     pub fn PyUnicode_FromStringAndSize(u: *const c_char, size: Py_ssize_t) -> *mut PyObject;
@@ -85,15 +82,6 @@ extern "C" {
         copy_null: c_int,
     ) -> *mut Py_UCS4;
     pub fn PyUnicode_AsUCS4Copy(unicode: *mut PyObject) -> *mut Py_UCS4;
-    #[cfg(not(Py_LIMITED_API))]
-    #[cfg_attr(PyPy, link_name = "PyPyUnicode_AsUnicode")]
-    pub fn PyUnicode_AsUnicode(unicode: *mut PyObject) -> *mut Py_UNICODE;
-    #[cfg(not(Py_LIMITED_API))]
-    #[cfg_attr(PyPy, link_name = "PyPyUnicode_AsUnicodeAndSize")]
-    pub fn PyUnicode_AsUnicodeAndSize(
-        unicode: *mut PyObject,
-        size: *mut Py_ssize_t,
-    ) -> *mut Py_UNICODE;
     #[cfg_attr(PyPy, link_name = "PyPyUnicode_GetLength")]
     pub fn PyUnicode_GetLength(unicode: *mut PyObject) -> Py_ssize_t;
     #[cfg_attr(PyPy, link_name = "PyPyUnicode_GetSize")]