diff --git a/R/RDKitMinimalLib/Compat.toml b/R/RDKitMinimalLib/Compat.toml
new file mode 100644
index 000000000000000..c4d66cf31e9cd89
--- /dev/null
+++ b/R/RDKitMinimalLib/Compat.toml
@@ -0,0 +1,4 @@
+[1]
+JSON = "0.21.1-0.21"
+RDKit_jll = "2021.9.2-2021"
+julia = "1.6.0-1"
diff --git a/R/RDKitMinimalLib/Deps.toml b/R/RDKitMinimalLib/Deps.toml
new file mode 100644
index 000000000000000..970890daaa4e3fd
--- /dev/null
+++ b/R/RDKitMinimalLib/Deps.toml
@@ -0,0 +1,3 @@
+[1]
+JSON = "682c06a0-de6a-54ab-a142-c8b1cf79cde6"
+RDKit_jll = "03d1d220-30e6-562a-9e1a-3062d7b56d75"
diff --git a/R/RDKitMinimalLib/Package.toml b/R/RDKitMinimalLib/Package.toml
new file mode 100644
index 000000000000000..9c281f9a6908056
--- /dev/null
+++ b/R/RDKitMinimalLib/Package.toml
@@ -0,0 +1,3 @@
+name = "RDKitMinimalLib"
+uuid = "44044271-7623-48dc-8250-42433c44e4b7"
+repo = "https://github.com/eloyfelix/RDKitMinimalLib.jl.git"
diff --git a/R/RDKitMinimalLib/Versions.toml b/R/RDKitMinimalLib/Versions.toml
new file mode 100644
index 000000000000000..439fec3f1f9995b
--- /dev/null
+++ b/R/RDKitMinimalLib/Versions.toml
@@ -0,0 +1,2 @@
+["1.0.2"]
+git-tree-sha1 = "790abcabd62da4a368591f8c6946220804573344"
diff --git a/Registry.toml b/Registry.toml
index eb9f9df15351a6a..4c636cd00c56090 100644
--- a/Registry.toml
+++ b/Registry.toml
@@ -1804,6 +1804,7 @@ some amount of consideration when choosing package names.
 43e2f499-f4c7-585f-8317-cbc2d9c3bf8f = { name = "RDKafka", path = "R/RDKafka" }
 43ec2cc1-0e50-5406-a854-b7ff8fdb8dad = { name = "ToStruct", path = "T/ToStruct" }
 43edad99-fa64-5e4f-9937-1c09a410b73f = { name = "InstantiateFromURL", path = "I/InstantiateFromURL" }
+44044271-7623-48dc-8250-42433c44e4b7 = { name = "RDKitMinimalLib", path = "R/RDKitMinimalLib" }
 44063525-382a-5b84-b7ca-976d099b8647 = { name = "NODAL", path = "N/NODAL" }
 4418983a-e44d-11e8-3aec-9789530b3b3e = { name = "Registrator", path = "R/Registrator" }
 442a2c76-b920-505d-bb47-c5924d526838 = { name = "FastGaussQuadrature", path = "F/FastGaussQuadrature" }