diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index a2d3ecf38..1572d74d2 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -7,6 +7,7 @@
 - Fix the impossibility to ``remove()`` a handler if an exception is raised while the sink' ``stop()`` function is called (`#237 <https://github.com/Delgan/loguru/issues/237>`_).
 - Fix file sink left in an unstable state if an exception occurred during ``retention`` or ``compression`` process (`#238 <https://github.com/Delgan/loguru/issues/238>`_).
 - Fix situation where changes made to ``record["message"]`` were unexpectedly ignored when ``opt(colors=True)``, causing "out-of-date" ``message`` to be logged due to implementation details (`#221 <https://github.com/Delgan/loguru/issues/221>`_).
+- Fix possible exception if a stream having an ``isatty()`` method returning ``True`` but not being compatible with ``colorama`` is used on Windows (`#249 <https://github.com/Delgan/loguru/issues/249>`_).
 
 
 `0.4.1`_ (2020-01-19)
diff --git a/loguru/_colorama.py b/loguru/_colorama.py
index ac9e80fa0..4662ab159 100644
--- a/loguru/_colorama.py
+++ b/loguru/_colorama.py
@@ -22,6 +22,9 @@ def should_wrap(stream):
     if os.name != "nt":
         return False
 
+    if stream is not sys.__stdout__ and stream is not sys.__stderr__:
+        return False
+
     from colorama.win32 import winapi_test
 
     return winapi_test()
diff --git a/tests/test_add_option_colorize.py b/tests/test_add_option_colorize.py
index c01ae1da7..7152fbca0 100644
--- a/tests/test_add_option_colorize.py
+++ b/tests/test_add_option_colorize.py
@@ -70,10 +70,17 @@ def patch_colorama(monkeypatch):
 
 @pytest.mark.parametrize("colorize", [True, False, None])
 @pytest.mark.parametrize("tty", [True, False])
-def test_colorize_stream_linux(patch_colorama, monkeypatch, colorize, tty):
-    monkeypatch.setattr(os, "name", "posix")
+@pytest.mark.parametrize("replace_original", [True, False])
+def test_colorize_stream(patch_colorama, monkeypatch, colorize, tty, replace_original):
     stream = Stream(tty)
-    logger.add(stream, format="<red>{message}</red>", colorize=colorize)
+
+    monkeypatch.delenv("TERM", raising=False)
+    monkeypatch.delenv("PYCHARM_HOSTED", raising=False)
+    monkeypatch.setattr(os, "name", "unix")
+    if replace_original:
+        monkeypatch.setattr(sys, "__stdout__", stream)
+
+    logger.add(stream, format="<red>{message}</red>", colorize=colorize, catch=False)
     logger.debug("Message")
 
     winapi_test = patch_colorama.win32.winapi_test
@@ -90,17 +97,23 @@ def test_colorize_stream_linux(patch_colorama, monkeypatch, colorize, tty):
 
 @pytest.mark.parametrize("colorize", [True, False, None])
 @pytest.mark.parametrize("tty", [True, False])
-def test_colorize_stream_windows(patch_colorama, monkeypatch, colorize, tty):
-    monkeypatch.setattr(os, "name", "nt")
+@pytest.mark.parametrize("replace_original", [True, False])
+def test_colorize_stream_windows(patch_colorama, monkeypatch, colorize, tty, replace_original):
     stream = Stream(tty)
-    logger.add(stream, format="<blue>{message}</blue>", colorize=colorize)
+
+    monkeypatch.delenv("TERM", raising=False)
+    monkeypatch.delenv("PYCHARM_HOSTED", raising=False)
+    monkeypatch.setattr(os, "name", "nt")
+    if replace_original:
+        monkeypatch.setattr(sys, "__stdout__", stream)
+
+    logger.add(stream, format="<blue>{message}</blue>", colorize=colorize, catch=False)
     logger.debug("Message")
-    writer = patch_colorama.AnsiToWin32().stream.write.called
 
     winapi_test = patch_colorama.win32.winapi_test
     stream_write = patch_colorama.AnsiToWin32().stream.write
 
-    if colorize or (colorize is None and tty):
+    if replace_original and (colorize or (colorize is None and tty)):
         assert winapi_test.called
         assert stream_write.called
     else: