diff --git a/packages/yarnpkg-pnp/sources/loader/hydrateRuntimeState.ts b/packages/yarnpkg-pnp/sources/loader/hydrateRuntimeState.ts
index 240eeaa8521a..3a3817f8eb0c 100644
--- a/packages/yarnpkg-pnp/sources/loader/hydrateRuntimeState.ts
+++ b/packages/yarnpkg-pnp/sources/loader/hydrateRuntimeState.ts
@@ -45,10 +45,13 @@ export function hydrateRuntimeState(data: SerializedState, {basePath}: HydrateRu
         // we only need this for packages that are used by the currently running script
         // this is a lazy getter because `ppath.join` has some overhead
         get packageLocation() {
-          // We use ppath.join instead of ppath.resolve because:
-          // 1) packageInformationData.packageLocation is a relative path when part of the SerializedState
-          // 2) ppath.join preserves trailing slashes
-          return resolvedPackageLocation || (resolvedPackageLocation = ppath.join(absolutePortablePath, packageInformationData.packageLocation));
+          // We keep /nix/store paths as they are
+          return resolvedPackageLocation || (packageInformationData.packageLocation.match('^/nix/store/')
+            ? (resolvedPackageLocation = packageInformationData.packageLocation)
+            // We use ppath.join instead of ppath.resolve because:
+            // 1) packageInformationData.packageLocation is a relative path when part of the SerializedState
+            // 2) ppath.join preserves trailing slashes
+            : (resolvedPackageLocation = ppath.join(absolutePortablePath, packageInformationData.packageLocation)));
         },
       }];
     }))];
diff --git a/packages/yarnpkg-pnp/sources/loader/makeApi.ts b/packages/yarnpkg-pnp/sources/loader/makeApi.ts
index 2a7fad67482f..685f54ce778c 100644
--- a/packages/yarnpkg-pnp/sources/loader/makeApi.ts
+++ b/packages/yarnpkg-pnp/sources/loader/makeApi.ts
@@ -491,10 +491,18 @@ export function makeApi(runtimeState: RuntimeState, opts: MakeApiOptions): PnpAp
     if (isPathIgnored(location) && !resolveIgnored)
       return null;
 
-    let relativeLocation = ppath.relative(runtimeState.basePath, location);
+    let relativeLocation
 
-    if (!relativeLocation.match(isStrictRegExp))
-      relativeLocation = `./${relativeLocation}` as PortablePath;
+
+    let boundryValue = ``
+    if (location.match('^/nix/store/')) {
+      relativeLocation = location
+      boundryValue = `/`
+    } else {
+      relativeLocation = ppath.relative(runtimeState.basePath, location);
+      if (!relativeLocation.match(isStrictRegExp))
+        relativeLocation = `./${relativeLocation}` as PortablePath;
+    }
 
     if (!relativeLocation.endsWith(`/`))
       relativeLocation = `${relativeLocation}/` as PortablePath;
@@ -508,7 +516,7 @@ export function makeApi(runtimeState: RuntimeState, opts: MakeApiOptions): PnpAp
       }
 
       return entry.locator;
-    } while (relativeLocation !== ``);
+    } while (relativeLocation !== boundryValue);
 
     return null;
   }