-
Notifications
You must be signed in to change notification settings - Fork 0
/
Copy pathcv-backup.html
1398 lines (1220 loc) · 72.2 KB
/
cv-backup.html
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Strict//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-strict.dtd">
<html xmlns="http://www.w3.org/1999/xhtml" lang="en" xml:lang="en">
<head>
<title>Nicholas Tatonetti | Curriculum Vitae</title>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
<link rel="shortcut icon" href="/files/tatonetti_favicon.ico" type="image/x-icon" />
<link rel="stylesheet" type"text/css" href="print.css" media="print">
<link rel="stylesheet" type"text/css" href="style.css" media="screen">
<style>
p.citation .authors {
}
p.citation .title {
text-decoration: underline;
display: block;
padding: 3px 0;
}
p.citation {
text-indent: 0;
}
</style>
</head>
<body>
<div class="main">
<span class="print-button">
<input type="button" onClick="window.print()" value="print"/>
</span>
<div class="title">
<h1>NICHOLAS TATONETTI, Ph.D.</h1>
Department of Biomedical Informatics, <br/>
Department of Systems Biology, &<br/>
Department of Medicine<br/>
Columbia University<br/>
622 West 168th St. PH20<br/>
New York, NY 10032<br/>
212 305 9104<br/>
[email protected]<br/>
<a href="http://tatonettilab.org">tatonettilab.org</a><br/>
</div>
<!-- EDUCATION -->
<h2>Education</h2>
<div class="section">
<div class="item">
<b>Stanford University</b>, Stanford, CA 2008-2012<br/>
<div class="indent">Ph.D. in Biomedical Informatics, June 2012</div>
<div class="indent">M.S. in Biomedical Informatics, December 2011</div>
</div>
<div class="item">
<b>Arizona State University</b>, Tempe, AZ 2005-2008<br/>
<div class="indent">B.S. <i>Summa Cum Laude</i> in Computational Mathematics, May 2008</div>
<div class="indent">B.S. <i>Summa Cum Laude</i> in Molecular Biosciences/Biotechnology, May 2008</div>
</div>
</div>
<h2>Professional Experience</h2>
<div class="section">
<p>
<b>Columbia University</b>, New York, NY<br/>
Associate Professor of Biomedical Informatics (in the Departments of Biomedical
Informatics, Systems Biology, and Medicine) (2019-present)<br/>
Herbert Irving Assistant Professor of Biomedical Informatics (in the Departments of Biomedical
Informatics, Systems Biology, and Medicine), 2012-2019<br/>
Director, Clinical Informatics, Herbert Irving Comprehensive Cancer Center, 2013-present<br/>
Co-Director, Bioinformatics, Department of Biomedical Informatics, 2017-present<br/>
Director, Clinical Informatics, Institute for Genomic Medicine, 2017-present
</p>
<p>
<b>Stanford University</b>, Stanford, CA<br/>
Department of Energy Office of Science Graduate Fellow in the Biomedical Informatics Training Program, 2008-2012.<br/>
<em>Doctoral Advisor:</em> Russ Altman, <br/>
<em>Doctoral Committee:</em> Atul Butte, Trevor Hastie, and Phillip Tsao, <br/>
<em>Dissertation Title:</em> "Data-driven Detection, Prediction, and Validation of Drug-Drug Interactions."
</p>
<!--
<p>
<b>Scientific Advisory Board Memberships</b><br/>
YouGene, Inc. (2013-)<br/>
Advera Health, Inc. (2012-)<br/>
</p>
-->
<p>
<b>Professional Society Memberships</b><br/>
American Medical Informatics Association (2011-)<br/>
American Society of Human Genetics (2016-)<br/>
American Society for Clinical Pharmacology and Therapeutics (2016-)<br/>
International Society for Computational Biology (2012-2014)<br/>
American Statistical Association (2013-2014)<br/>
</p>
</div>
<!-- PUBLICATIONS -->
<h2>Peer-Reviewed Publications and Pre-prints</h2>
<div class="section printhide">
<a href="https://scholar.google.com/citations?user=ejoWKqsAAAAJ&hl=en">Google Scholar</a>
<a href="https://www.ncbi.nlm.nih.gov/myncbi/nicholas.tatonetti.1/bibliography/public/">NCBI bibliography</a>
</div>
<div class="section">
<!-- <p>
<strong><em>2020</em></strong>
</p> -->
<span class="author_icon">FA</span>
<p class="citation">
<span class="authors">Nicholas P Tatonetti and Noemie Elhadad</span>
<span class="title">Fine-scale genetic ancestry as a potential new tool for precision medicine</span>
<span class="journal"><em>Nature Medicine</em> 2021</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Nicholas P Giangreco, Guillaume Lebreton, Susan Restaino, Mary Jane Farr, Emmanuel Zorn, Paolo C Colombo, Jignesh Patel, Ryan Levine, Lauren Truby, Rajesh Kumar Soni, Pascal Leprince, Jon Kobashigawa, Nicholas P Tatonetti*, Barry M Fine*</span>
<span class="title">Plasma kallikrein predicts primary graft dysfunction after heart transplant</span>
<span class="journal"><em>The Journal of Heart and Lung Transplantation</em> 2021</span>
</p>
<p class="citation">
<span class="authors">Theresa A Koleck, Nicholas P Tatonetti, Suzanne Bakken, Shazia Mitha, Morgan M Henderson, Maureen George, Christine Miaskowski, Arlene Smaldone, Maxim Topaz</span>
<span class="title">Identifying Symptom Information in Clinical Notes Using Natural Language Processing</span>
<span class="journal"><em>Nursing research</em> 2020</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">ER Silver, HQ Truong, S Ostvar, C Hur, and <strong>NP Tatonetti</strong>,</span>
<span class="title">Association of Neighborhood Deprivation Index With Success in Cancer Care Crowdfunding</span>
<span class="journal"><em>JAMA network open</em> 3 (12), e2026946-e2026946 (2020)</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">V Ramlall, J Zucker, and <strong>NP Tatonetti</strong>,</span>
<span class="title">Melatonin is significantly associated with survival of intubated COVID-19 patients</span>
<span class="journal"><em>medRxiv</em> 2020</span>
</p>
<p class="citation">
<span class="authors">DJ Butler, CMozsary, C Meydan, DC Danko, J Foox, ..., Michael Zeitz, Vijendra Ramlall, Undina Gisladottir, ... <strong>NP Tatonetti</strong>, M Imielinski, H Rennert, C Mason,</span>
<span class="title">Host, Viral, and Environmental Transcriptome Profiles of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),</span>
<span class="journal"><em>Nature Communications</em> 2020 <em>(In Press)</em></span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">M Zietz and <strong>NP Tatonetti</strong>,</span>
<span class="title">Associations between blood type and COVID-19 infection, intubation, and death</span>
<span class="journal"><em>Nature Communications</em> 2020 11 (1), 1-6</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">P Chandak and <strong>NP Tatonetti</strong>,</span>
<span class="title">Using Machine Learning to Identify Adverse Drug Effects Posing Increased Risk to Women</span>
<span class="journal"><em>Patterns</em> 2020 1 (7), 100108</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Vijendra Ramlall, Phyllis M Thangaraj, Cem Meydan, Jonathan Foox, Daniel Butler, Jacob Kim, Ben May, Jessica K De Freitas, Benjamin S Glicksberg, Christopher E Mason, <strong>Nicholas P Tatonetti</strong>, Sagi D Shapira</span>
<span class="title">Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection</span>
<span class="journal"><em>Nature Medicine</em> 2020;10.1038/s41591-020-1021-2. doi:10.1038/s41591-020-1021-2</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">N Giangreco, JE Elias, and <strong>NP Tatonetti</strong>,</span>
<span class="title">No population left behind: improving pediatric drug safety using informatics and systems biology</span>
<span class="journal"><em>British Journal of Clinical Pharmacology</em> 2020</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">S Ostvar, H Troung, ER Silver, CJ Lightdale, C Hur, and <strong>NP Tatonetti</strong>,</span>
<span class="title">Transfer learning from simulations improves the classification of OCT images of glandular epithelia</span>
<span class="journal"><em>bioRxiv</em> 2020</span>
</p>
<p class="citation">
<span class="authors">A Krigel, <strong>NP Tatonetti</strong>, AI Neugut, B Lebwohl</span>
<span class="title">No Increased Risk of Colorectal Adenomas in Spouses of Patients with Colorectal Neoplasia</span>
<span class="journal"><em>Clinical Gastroenterology and Hepatology</em> 18 (2), 509-510</span>
</p>
<p class="citation">
<span class="authors">SE Brenner, ML Bulyk, DC Crawford, AA Morgan, P Radivojac, <strong>NP Tatonetti</strong>,</span>
<span class="title">Precision Medicine: Addressing the Challenges of Sharing, Analysis, and Privacy at Scale</span>
<span class="journal"><em>Pacific Symposium on Biocomputing</em> (2020) 25, 547-550</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">PM Thangaraj, <strong>N Tatonetti</strong></span>
<span class="title">Medical data and machine learning improve power of stroke genome-wide association studies.</span>
<span class="journal"><em>BioRxiv</em> <em>(In preparation)</em></span>
</p>
<!-- <p>
<strong><em>2019</em></strong>
</p> -->
<p class="citation">
<span class="authors">BS Glicksberg, B Oskotsky, PM Thangaraj, N Giangreco, MA Badgeley, KW Johnson, D Datta, VA Rudrapatna, N Rappoport, MM Shervey, R Miotto, TC Goldstein, E Rutenberg, R Frazier, N Lee, S Israni, R Larsen, B Percha, Li Li, JT Dudley, NP Tatonetti, AJ Butte</span>
<span class="title">PatientExploreR: an extensible application for dynamic visualization of patient clinical history from electronic health records in the OMOP common data model</span>
<span class="journal"><em>Bioinformatics</em> 35 (21), 4515-4518</span>
</p>
<p class="citation">
<span class="authors">O Lyudovyk, Y Shen, <strong>NP Tatonetti</strong>, SJ Hsiao, MM Mansukhani, C Weng</span>
<span class="title">Pathway analysis of genomic pathology tests for prognostic cancer subtyping</span>
<span class="journal"><em>Journal of biomedical informatics</em> 98, 103286</span>
</p>
<p class="citation">
<span class="authors">BD De Oliveira, K Xu, TH Shen, M Callahan, K Kiryluk, VD D’Agati, NP Tatonetti, J Barasch, P Devarajan</span>
<span class="title">Molecular nephrology: types of acute tubular injury</span>
<span class="journal"><em>Trends in pharmacological sciences</em></span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">AO Basile, A Yahi, <strong>N Tatonetti</strong></span>
<span class="title">Artificial intelligence for drug toxicity and safety</span>
<span class="journal"><em>Trends in pharmacological sciences</em></span>
</p>
<p class="citation">
<span class="authors">FCG Polubriaginof, P Ryan, H Salmasian, AW Shapiro, A Perotte, Monika M Safford, G Hripcsak, S Smith, NP Tatonetti, DK Vawdrey</span>
<span class="title">Challenges with quality of race and ethnicity data in observational databases</span>
<span class="journal"><em>JAMIA</em> 26 (8-9), 730-736</span>
</p>
<p class="citation">
<span class="authors">SC Ahalt, CG Chute, K Fecho, G Glusman, J Hadlock, CO Taylor, ER Pfaff, PN Robinson, H Solbrig, C Ta, <strong>N Tatonetti</strong>, C Weng, Biomedical Data Translator Consortium</span>
<span class="title">Clinical data: sources and types, regulatory constraints, applications</span>
<span class="journal"><em>Clinical and translational science</em> 12 (4), 329</span>
</p>
<p class="citation">
<span class="authors">MR Boland, <strong>NP Tatonetti</strong></span>
<span class="title">Attention Deficit-Hyperactivity Disorder and Month of School Enrollment</span>
<span class="journal"><em>NEJM</em> 380(7): 692-693, Feb 2019.</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">V Ramlall, KM Quinnies, R Vanguri, T Lorberbaum, DB Goldstein, <strong>N Tatonetti</strong></span>
<span class="title">Predicting the genetic ancestry of 2.6 million New York City patients using clinical data</span>
<span class="journal"><em>BioRxiv</em>768440 <em>(In revision)</em></span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Z Liu, <strong>N Tatonetti</strong></span>
<span class="title">Familial relationships in electronic health records (EHR) v2</span>
<span class="journal"><em>BioRxiv</em>731976</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">JD Romano, H Li, R Realubit, C Karan, <strong>NP Tatonetti</strong></span>
<span class="title">Discovering therapeutic activities from venoms using differential gene expression</span>
<span class="journal"><em>BioRxiv</em>699280 <em>(In preparation)</em></span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">NP Giangreco, B Fine, <strong>NP Tatonetti</strong></span>
<span class="title">cohorts: A Python package for clinical ‘omics data management</span>
<span class="journal"><em>BioRxiv</em>626051</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">P Thangaraj, B Kummer, T Lorberbaum, M Elkind, <strong>N Tatonetti</strong></span>
<span class="title">Comparative analysis of EHR-based stroke phenotyping methods, their applications, and interpretation</span>
<span class="journal"><em>BioRxiv</em>565671 <em>(In preparation)</em></span>
</p>
<p class="citation">
<span class="authors">A Krigel, <strong>NP Tatonetti</strong>, AI Neugut, B Lebwohl</span>
<span class="title">No Increased Risk of Colorectal Adenomas in Spouses of Patients with Colorectal Neoplasia</span>
<span class="journal"><em>Clinical Gastroenterology and Hepatology</em></span>
</p>
<p class="citation">
<span class="authors">AS Faye, F Polubriaginof, PHR Green, DK Vawdrey, <strong>N Tatonetti</strong>, B Lebwohl</span>
<span class="title">Low Rates of Screening for Celiac Disease Among Family Members</span>
<span class="journal"><em>Clinical Gastroenterology and Hepatology</em> 17 (3), 463-468</span>
</p>
<p class="citation">
<span class="authors">BS Glicksberg, B Oskotsky, N Giangreco, PM Thangaraj, V Rudrapatna, D Datta, R Frazier, N Lee, R Larsen, <strong>NP Tatonetti</strong>, AJ Butte</span>
<span class="title">ROMOP: a light-weight R package for interfacing with OMOP-formatted electronic health record data</span>
<span class="journal"><em>JAMIA Open</em> 2 (1), 10-14</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">JD Romano, <strong>NP Tatonetti</strong></span>
<span class="title">Informatics and computational methods in natural product drug discovery: A review and perspectives</span>
<span class="journal"><em>Frontiers in Genetics</em> 10, 368</span>
</p>
<!-- <p>
<strong><em>2018</em></strong>
</p> -->
<p class="citation">
<span class="authors">F Spagnolo, P Cristofari, <strong>NP Tatonetti</strong>, LR Ginzburg, DE Dykhuizen</span>
<span class="title">Pathogen population structure can explain hospital outbreaks</span>
<span class="journal"><em>The ISME journal</em> 12 (12), 2835</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">CN Ta, M Dumontier, G Hripcsak, <strong>NP Tatonetti</strong>, C Weng</span>
<span class="title">Columbia Open Health Data, clinical concept prevalence and co-occurrence from electronic health records</span>
<span class="journal"><em>Scientific data</em> 5, 180273</span>
</p>
<p class="citation">
<span class="authors">K Shameer, MM Perez-Rodriguez, R Bachar, LL, A Johnson, KW Johnson, BS Glicksberg, MR Smith, B Readhead, J Scarpa, J Jebakaran, P Kovatch, S Lim, W Goodman, DL Reich, A Kasarskis, <strong>NP Tatonetti</strong>, JT Dudley</span>
<span class="title">Pharmacological risk factors associated with hospital readmission rates in a psychiatric cohort identified using prescriptome data mining</span>
<span class="journal"><strong>BMC medical informatics and decision making</strong> 18 (3), 79</span>
</p>
<p class="citation">
<span class="authors">E Castillero, ZA Ali, H Akashi, N Giangreco, C Wang, EJ Stöhr, R Ji, X Zhang, N Kheysin, JS Park, S Hegde, S Patel, S Stein, C Cuenca, D Leung, S Homma, NP Tatonetti, VK Topkara, K Takeda, PC Colombo, Y Naka, HL Sweeney, PC Schulze, I George</span>
<span class="title">Tissue‐Specific Analysis of Pharmacological Pathways</span>
<span class="journal"><em>American Journal of Physiology-Heart and Circulatory Physiology</em> (315) 5 H1463-H1476</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Y Hao, K Quinnies, R Realubit, C Karan, <strong>NP Tatonetti</strong></span>
<span class="title">Tissue‐Specific Analysis of Pharmacological Pathways</span>
<span class="journal"><em>CPT: pharmacometrics & systems pharmacology</em> 7 (7), 453-463</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">F Polubriaginof, R Vanguri, K Quinnies, G Belbin, A Yahi, H Salmasian, T Lorberbaum, V Nwankwo, L Li, M Shervey, P Glowe, I Ionita-Laza, M Simmerling, G Hripcsak, S Bakken, D Goldstein, K Kiryluk, E Kenny, J Dudley, DK Vawdrey, <strong>NP Tatonetti</strong></span>
<span class="title">Disease heritability inferred from familial relationships reported in medical records</span>
<span class="journal"><em>Cell</em> 173 (7), 1692-1704. e11</span>
</p>
<span class="author_icon">SA</span>
<p class="citation">
<span class="authors"><strong>NP Tatonetti</strong></span>
<span class="title">Science as a Culinary Art: How Data Science and Informatics Will Change Knowledge Discovery for Everyone</span>
<span class="journal"><em>Annual Review of Biomedical Data Science 1</em>, iv-vi</span>
</p>
<p class="citation">
<span class="authors">AS Faye, F Polubriaginof, PH Green, DK Vawdrey, <strong>N Tatonetti</strong>, B Lebwohl</span>
<span class="title">Low Rates of Screening for Celiac Disease Among Family Members; Analysis of Algorithm-Identified Familial Relationships</span>
<span class="journal"><em>Gastroenterology</em> 154 (6), S-674-S-675</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">MR Boland, F Polubriaginof, <strong>NP Tatonetti</strong></span>
<span class="title">A machine learning algorithm to classify FDA Category C drugs.</span>
<span class="journal"><em>Clinical Pharmacology & Therapeutics</em> 103, S10-S10</span>
</p>
<span class="author_icon">SA</span>
<p class="citation">
<span class="authors"><strong>NP Tatonetti</strong></span>
<span class="title">The Next Generation of Drug Safety Science: Coupling Detection, Corroboration, and Validation to Discover Novel Drug Effects and Drug–drug Interactions</span>
<span class="journal"><em>Clinical Pharmacology & Therapeutics</em> 103 (2), 177-179</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">A Yahi, R Vanguri, N Elhadad, <strong>NP Tatonetti</strong></span>
<span class="title">Generative Adversarial Networks for Electronic Health Records: A Framework for Exploring and Evaluating Methods for Predicting Drug-Induced Laboratory Test Trajectories</span>
<span class="journal"><em>NIPS ML4H 2017</em></span>
</p>
<p class="citation">
<span class="authors">Knowledge Base workgroup of the Observational Health Data Sciences and Informatics (OHDSI) collaborative,</span>
<span class="title">Large-scale adverse effects related to treatment evidence standardization (LAERTES): an open scalable system for linking pharmacovigilance evidence sources with clinical data</span>
<span class="journal"><em>Journal of Biomedical Semantics</em> 8, 1-15; 10.1186/s13326-017-0115-3</span>
</p>
<p class="citation">
<span class="authors">N Macesic, F Polubriaginof, <strong>NP Tatonetti</strong></span>
<span class="title">Machine learning: novel bioinformatics approaches for combating antimicrobial resistance.</span>
<span class="journal"><em>Current Opinion in Infectious Diseases</em> 2017/9/12</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">R Moskovitch, F Polubriaginof, A Weiss, P Ryan, <strong>N Tatonetti</strong></span>
<span class="title">Procedure Prediction from Symbolic Electronic Health Records via Time Intervals Analytics</span>
<span class="journal"><em>Journal of Biomedical Informatics</em> 2017/8/17</span>
</p>
<p class="citation">
<span class="authors">PJ Kennel, A Saha, DA Maldonado, RGivens, DL Brunjes, ECastillero, X Zhang, RJi, A Yahi, I George, DM Mancini, A Koller, B Fine, E Zorn, PC Colombo, <strong>N Tatonetti</strong>, EI Chen, PC Schulze</span>
<span class="title">Serum exosomal protein profiling for the non-invasive detection of cardiac allograft rejection</span>
<span class="journal"><em>The Journal of Heart and Lung Transplantation</em> 2017/8/17</span>
</p>
<span class="author_icon">SA</span>
<p class="citation">
<span class="authors"><strong>NP Tatonetti</strong></span>
<span class="title">Translational medicine in the Age of Big Data</span>
<span class="journal"><em>Briefings in Bioinformatics</em> 2017/10/12</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">MR Boland, F Polubriaginof, <strong>NP Tatonetti</strong></span>
<span class="title">Development of A Machine Learning Algorithm to Classify Drugs Of Unknown Fetal Effect</span>
<span class="journal"><em>Scientific Reports</em> 7 (1), 12839</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">MR Boland, P Parhi, L Li, R Miotto, R Carroll, U Iqbal, PA Nguyen, M Schuemie, SC You, D Smith, S Mooney, P Ryan, YJ Li, RW Park, J Denny, JT Dudley, G Hripcsak, P Gentine, and <strong>NP Tatonetti</strong></span>
<span class="title">Uncovering exposures responsible for birth season–disease effects: a global study</span>
<span class="journal"></em>Journal of the American Medical Informatics Association</em> 2017/9/28</span>
</p>
<!-- <p>
<strong><em>2017</em></strong>
</p> -->
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">MR Boland, P Parhi, P Gentine, <strong>NP Tatonetti</strong></span>
<span class="title">Climate classification is an important factor in assessing quality-of-care across hospitals</span>
<span class="journal"><em>Scientific Reports</em> 7 (1), 4948</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">R Moskovitch, H Choi, G Hripcsak, <strong>N Tatonetti</strong></span>
<span class="title">Prognosis of clinical outcomes with temporal patterns and experiences with one class feature selection</span>
<span class="journal"><em>IEEE/ACM transactions on computational biology and bioinformatics</em> 2017/5/1 14 (3) 555-563</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">T Lorberbaum, <strong>N Tatonetti</strong></span>
<span class="title">Reply: Combination Therapy With Ceftriaxone and Lansoprazole, Acquired Long QT Syndrome and Torsades de Pointes Risk</span>
<span class="journal"><em>Journal of the American College of Cardiology</em> 69 (14), 1877-1878</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">MR Boland, KJ Karczewski, <strong>NP Tatonetti</strong></span>
<span class="title">Ten Simple Rules to Enable Multi-site Collaborations through Data Sharing</span>
<span class="journal"><em>PLOS Computational Biology</em> 13 (1), e1005278; 10.1371/journal.pcbi.1005278</span>
</p>
<!-- <p>
<strong><em>2016</em></strong>
</p> -->
<p class="citation">
<span class="authors">C Deng, MR Lipstein, L Scotto, XO Jirau Serrano, MA Mangone, S Li, J Vendome, Y Hao, X Xu, SX Deng, RB Realubit, <strong>NP Tatonetti</strong>, C Karan, S Lentzsch, DA Fruman, B Honig, D W Landry, OA O’Connor</span>
<span class="title">Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies</span>
<span class="journal"><em>Blood</em> 129 (1), 88-99; 10.1182/blood-2016-08-731240</span>
</p>
<p class="citation">
<span class="authors">LK Xu, P Rosenstiel, N Paragas, C Hinze, X Gao, TH Shen, M Werth, C Forster, R Deng, E Bruck, RW Boles, A Tornato, T Gopal, M Jones, J Konig, J Stauber, V D’Agati, H Erdjument-Bromage, S Saggi, G Wagener, KM Schmidt-Ott, <strong>NP Tatonetti</strong>, P Tempst, JA Oliver, P Guarnieri, J Barasch</span>
<span class="title">Unique transcriptional programs identify subtypes of AKI</span>
<span class="journal"><em>Journal of the American Society of Nephrology</em> (2016) 10.1681/ASN.2016090974</span>
</p>
<p class="citation">
<span class="authors">JM Banda, L Evans, RS Vanguri, <strong>NP Tatonetti</strong>, PB Ryan, NH Shah</span>
<span class="title">A curated and standardized adverse drug event resource to accelerate drug safety research</span>
<span class="journal"><em>Scientific Data</em> (3) 2016</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Lorberbaum T, Sampson KJ, Chang JB, Iyer V, Woosley RL, Kass RS, <strong>Tatonetti NP</strong></span>
<span class="title">Coupling data mining and laboratory experiments to discover drug interactions causing QT prolongation</span>
<span class="journal"><em>Journal of the American College of Cardiology</em> 68 (16) 1756-1764; 10.1016/j.jacc.2016.07.761</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Hao Y and <strong>Tatonetti NP</strong></span>
<span class="title">Predicting G Protein-Coupled Recetpor Downstream Signaling by Tissue Expression</span>
<span class="journal"><em>Bioinformatics</em> Bioinformatics 32 (22), 3435-3443; 10.1093/bioinformatics/btw510</span>
</p>
<p class="citation">
<span class="authors">KW Johnson, K Shameer, A Yahi, R Miotto, D Ricks, J Jebakaran, P Kovatch, P Sengupta, DL Reich, A Kasarskis, S Pinney, <strong>NP Tatonetti</strong>, Joel T Dudley</span>
<span class="title">Pharmacological Factors Associated With Congestive Heart Failure Hospital Readmission: A Case-Study Using 15,768 Heart Failure Patients From Two Health Systems</span>
<span class="journal"><em>Circulation</em> 134 (Suppl 1), A19489-A19489;</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Chang JB, Quinnies KM, Realubit R, Karan C, Rand JH, <strong>Tatonetti NP</strong></span>
<span class="title">A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient</span>
<span class="journal"><em>Scientific Reports</em> 6/29387 doi:10.1038/srep29387</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Moskovitch R, Choi H, Hripcsak G, <strong>Tatonetti N</strong>,</span>
<span class="title">Prognosis of Clinical Outcomes with Temporal Patterns and Experiences with One Class Feature Selection</span>
<span class="journal"><em>IEEE/ACM Transactions on Computational Biology and Bioinformatics</em> 14 July 2016; 10.1109/TCBB.2016.2591539</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">Boland MR, <strong>Tatonetti NP</strong>,</span>
<span class="title">Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review.</span>
<span class="journal"><em>The Pharmacogenomics Journal</em> 12 July 2016; doi: 10.1038/tpj.2016.48</span>
</p>
<p class="citation">
<span class="authors">Nissim N, Boland MR, <strong>Tatonetti NP</strong>, Elovici Y, Hripcsak G, Shahar Y, Moskovitch R,</span>
<span class="title">Improving Condition Severity Classification with an Efficient Active Learning Based Framework.</span>
<span class="journal"><em>J Biomed Inform.</em> 2016 Mar 22. pii: S1532-0464(16)30007-7. doi: 10.1016/j.jbi.2016.03.016</span>
</p>
<p class="citation">
<span class="authors">Hoffman KB, Dimbil M, <strong>Tatonetti NP</strong>, Kyle RF,</span>
<span class="title">A Pharmacovigilance Signaling System Based on FDA Regulatory Action and Post-Marketing Adverse Event Reports.</span>
<span class="journal"><em>Drug Safety</em> 2016 Mar 5</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">T Lorberbaum, KJ Sampson, RL Woosley, RS Kass, <strong>NP Tatonetti</strong>,</span>
<span class="title">An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval</span>
<span class="journal"><em>Drug Safety</em> pp 1-9 (2016) doi:10.1007/s40264-016-0393-1</span>
</p>
<p class="citation">
<span class="authors">BA Kidd, A Wroblewska, MR Boland, J Agudo, M Merad, <strong>NP Tatonetti</strong>, BD Brown, JT Dudley</span>
<span class="title">Mapping the effects of drugs on the immune system</span>
<span class="journal"><em>Nature biotechnology</em> 34 (1), 47-54 (2016)</span>
</p>
<p class="citation">
<span class="authors">KB Hoffman, M Dimbil, RF Kyle, <strong>NP Tatonetti</strong>, CB Erdman, A Demakas, D Chen, BM Overstreet</span>
<span class="title">A Drug Safety Rating System Based on Postmarketing Costs Associated with Adverse Events and Patient Outcomes</span>
<span class="journal"><em>Journal of managed care & specialty pharmacy</em> (2015)</span>
</p>
<!-- <p>
<strong><em>2015</em></strong>
</p> -->
<p class="citation">
<span class="authors">C Deng, M Lipstein, L Scotto, Y Hao, <strong>NP Tatonetti</strong>, M Mangone, S Li</span>
<span class="title">Disruption of the mTOR-eIF4F Axis By Selectively Targeting PI3Kdelta and Proteasome 2015 Potently Inhibits Cap Dependent Translation of c-Myc in Aggressive Lymphomas</span>
<span class="journal"><em>Blood</em> 126 (23), 593-593 2015</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">JD Romano, <strong>NP Tatonetti</strong>,</span>
<span class="title">VenomKB, a new knowledge base for facilitating the validation of putative venom therapies</span>
<span class="journal"><em>ScientificData</em> 2 (2015) doi:10.1038/sdata.2015.65</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">MR Boland, A Jacunski, T Lorberbaum, JD Romano, R Moskovitch, <strong>NP Tatonetti</strong></span>
<span class="title">Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms</span>
<span class="journal"><em>WIREs Syst Biol Med.</em> (2015) doi: 10.1002/wsbm.1323</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">A Jacunski, S Dixon, <strong>NP Tatonetti</strong>,</span>
<span class="title">Connectivity homology enables inter-species network models of synthetic lethality</span>
<span class="journal"><em>PLOS Computational Biology</em> (2015) 11(10): e1004506. doi:10.1371/journal.pcbi.1004506</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">MR Boland, Z Shahn, D Madigan, G Hripcsak, <strong>NP Tatonetti</strong>,</span>
<span class="title">Birth Month Affects Lifetime Disease Risk: A Phenome-Wide Method</span>
<span class="journal"><em>Journal of the American Medical Informatics Association</em> (2015)</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">S Vilar, T Lorberbaum, G Hripcsak, <strong>NP Tatonetti</strong>,</span>
<span class="title">Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling</span>
<span class="journal"><em>PLOS One</em> (2015) 10 (6), e0129974</span>
</p>
<p class="citation">
<span class="authors">S Ayvaz, J Horn, O Hassanzadeh, Q Zhu, J Stan, <strong>NP Tatonetti</strong>, S Vilar, M Brochhausen, M Samwald, M Rastegar-Mojarad, M Dumontier, RD Boyce</span>
<span class="title">Toward a complete dataset of drug–drug interaction information from publicly available sources</span>
<span class="journal"><em>Journal of Biomedical Informatics</em> (2015) 55, 206-217</span>
</p>
<p class="citation">
<span class="authors">MR Boland, <strong>NP Tatonetti</strong>, G Hripcsak,</span>
<span class="title">Development and validation of a classification approach for extracting severity automatically from electronic health records</span>
<span class="journal"><em>Journal of Biomedical Semantics</em> (2015) 6 (1), 14</span>
</p>
<p class="citation">
<span class="authors">S Vilar, <strong>NP Tatonetti</strong>, G Hripcsak,</span>
<span class="title">3D Pharmacophoric Similarity improves Multi Adverse Drug Event Identification in Pharmacovigilance</span>
<span class="journal"><em>Scientific Reports</em> (2015) 5</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">T Lorberbaum, M Nasir, MJ Keiser, S Vilar, G Hripcsak, <strong>NP Tatonetti</strong></span>
<span class="title">Systems pharmacology augments drug safety surveillance</span>
<span class="journal"><em>Clinical Pharmacology & Therapeutics</em> (2015) 97 (2), 151-158</span>
</p>
<p class="citation">
<span class="authors">KB Hoffman, AR Demakas, M Dimbil, <strong>NP Tatonetti</strong>, CB Erdman</span>
<span class="title">Stimulated Reporting: The Impact of US Food and Drug Administration-Issued Alerts on the Adverse Event Reporting System (FAERS)</span>
<span class="journal"><em>Drug Safety</em> (2014) 37 (11), 971-980</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">R Moskovitch, C Walsh, G Hripcsak, <strong>N Tatonetti</strong></span>
<span class="title">Prediction of biomedical events via time intervals mining</span>
<span class="journal"><em>ACM KDD Workshop on Connected Health in Big Data Era</em> 2014</span>
</p>
<p class="citation">
<span class="authors">R D Boyce, P B Ryan, G N Norén, M J Schuemie, C Reich, J Duke, <strong>N P Tatonetti</strong>, G Trifiro, R Harpaz, J M Overhage, A G Hartzema, M Khayter, E A Voss, C G Lambert, V Huser, M Dumontier</span>
<span class="title">Bridging islands of information to establish an integrated knowledge base of drugs and health outcomes of interest</span>
<span class="journal"><em>Drug Safety</em> 37 (8), 557-567</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">S Vilar, E Uriarte, L Santana, C Friedman, <strong>NP Tatonetti</strong>,</span>
<span class="title">State of the Art and Development of a New Drug-Drug Interaction Large Scale Predictor Based on 3D Pharmacophoric Similarity</span>
<span class="journal"><em>Current Drug Metabolism</em> 15 (5), 490-501</span>
</p>
<p class="citation">
<span class="authors">S Vilar, PB Ryan, D Madigan, PE Stang, MJ Schuemie, C Friedman, NP Tatonetti, G Hripcsak</span>
<span class="title">Similarity‐Based Modeling Applied to Signal Detection in Pharmacovigilance</span>
<span class="journal"><em>CPT: pharmacometrics & systems pharmacology</em> 3 (9) 1-9 2014</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">S Vilar, E Uriarte, L Santana, T Lorberbaum, G Hripcsak, C Friedman, <strong>NP Tatonetti</strong>,</span>
<span class="title">Similarity-based modeling in large-scale prediction of drug-drug interactions</span>
<span class="journal"><em>Nature Protocols</em> (2014 Vol 9 Issue 9, 2147-2168)</span>
</p>
<p class="citation">
<span class="authors">MJ Matos, S Vilar, S Kachler, A Fonseca, L Santana, E Uriarte, F Borges, <strong>NP Tatonetti</strong>, KN Klotz.</span>
<span class="title">Insight into the Interactions between Novel Coumarin Derivatives and Human A3 Adenosine Receptors.</span>
<span class="journal"><em>ChemMedChem</em> 2014/7/18</span>
</p>
<p class="citation">
<span class="authors">Boyce RD, Ryan PB, Norén GN, Schuemie MJ, Reich C, Duke J, <strong>Tatonetti NP</strong>, Trifirò G, Harpaz R, Overhage JM, Hartzema AG, Khayter M, Voss EA, Lambert CG, Huser V, Dumontier M.</span>
<span class="title">Bridging Islands of Information to Establish an Integrated Knowledge Base of Drugs and Health Outcomes of Interest.</span>
<span class="journal"><em>Drug Safety</em> 2014 Jul 2.</span>
</p>
<p class="citation">
<span class="authors">Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, <strong>Tatonetti NP</strong>, Slusher BS, Stockwell BR.</span>
<span class="title">Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.</span>
<span class="journal"><em>eLife</em> 2014 May 20;3:e02523. doi: 10.7554/eLife.02523.</span>
</p>
<p class="citation">
<span class="authors">ZA Ali, S Poludasu, YH Qureshi, P Krishnan, AA Ali, <strong>N Tatonetti</strong>, P Downey, A Zalewski, T Nazif, I George, A Mandava, U Baber, G Dangas, R Mehran, AS Kini, and SK Sharma,</span>
<span class="title">Impact of major bleeding on long-term mortality in anemic versus nonanemic patients undergoing percutaneous coronary intervention using bivalirudin,</span>
<span class="journal"><em>The American journal of cardiology</em> 113, 1481–1486 (2014).</span>
</p>
<p class="citation">
<span class="authors">L Li, DJ Ruau, CJ Patel, SC Weber, R Chen, <strong>NP Tatonetti</strong>, JT Dudley, and AJ Butte,</span>
<span class="title">Disease Risk Factors Identified Through Shared Genetic Architecture and Electronic Medical Records,</span>
<span class="journal"><em>Science Translational Medicine</em> 6, 234ra57 (2014).</span>
</p>
<p class="citation">
<span class="authors">GL Delogu, S Serra, E Quezada, E Uriarte, S Vilar, NP Tatonetti, and D Viña,</span>
<span class="title">Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins,</span>
<span class="journal"><em>ChemMedChem</em> (2014), doi:10.1002/cmdc.201402010.</span>
</p>
<p class="citation">
<span class="authors">MJ Matos, S Vilar, V Garcia-Morales, <strong>NP Tatonetti</strong>, E Uriarte, L Santana, D Vina</span>
<span class="title">Insight into the Functional and Structural Properties of 3‐Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition.</span>
<span class="journal"><em>ChemMedChem</em> (2014) Apr 8</span>
</p>
<p class="citation">
<span class="authors">KB Hoffman, M Dimbil, CB Erdman, <strong>NP Tatonetti</strong>, BM Overstreet</span>
<span class="title">The Weber Effect and the United States Food and Drug Administration’s Adverse Event Reporting System (FAERS): Analysis of Sixty-Two Drugs Approved from 2006 to 2010.</span>
<span class="journal"><em>Drug Safety</em> (2014) Vol 37 Iss 4 pp 283-294</span>
</p>
<p class="citation">
<span class="authors">MJ Matos, P Janeiro, RM Gonzalez Franco, S Vilar, <strong>NP Tatonetti</strong>, L Santana, E Uriarte, F Borges, JA Fontenla, D Vina,</span>
<span class="title">Synthesis, pharmacological study and docking calculations of new benzo [f] coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases.</span>
<span class="journal"><em>Future medicinal chemistry</em> (2014) Vol 6 Iss 4 pp 371-383</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">KJ Karczewski, M Snyder, RB Altman, <strong>NP Tatonetti</strong>,</span>
<span class="title">Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association.</span>
<span class="journal"><em>PLOS Genetics</em> (2014) 10(2): e1004122. doi:10.1371/journal.pgen.1004122</span>
</p>
<p class="citation">
<span class="authors">KJ Karczewski, GH Fernald, AR Martin, M Snyder, <strong>NP Tatonetti</strong>, JT Dudley,</span>
<span class="title">STORMSeq: An Open-Source, User-Friendly Pipeline for Processing Personal Genomics Data in the Cloud.</span>
<span class="journal"><em>PLOS One</em> (2014) 9 (1), e84860</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">X Sun, S Vilar, <strong>NP Tatonetti</strong>,</span>
<span class="title">High-Throughput Methods for Combinatorial Drug Discovery.</span>
<span class="journal"><em>Science Translational Medicine</em> (2013), 5 (205), 205rv1-205rv1.</span>
</p>
<span class="author_icon">LA</span>
<p class="citation">
<span class="authors">A Jacunski, <strong>NP Tatonetti</strong>,</span>
<span class="title">Connecting the Dots: Applications of Network Medicine in Pharmacology and Disease.</span>
<span class="journal"><em>Clinical Pharmacology & Therapeutics</em> (2013).</span>
</p>
<p class="citation">
<span class="authors">MJ Matos, S Vilar, <strong>NP Tatonetti</strong>, L Santana, E Uriarte,</span>
<span class="title">Comparative study of the 3-phenylcoumarin scaffold: synthesis, X-ray structural analysis and semiempirical calculations of a selected series of compounds.</span>
<span class="journal"><em>Journal of Molecular Structure</em> (2013).</span>
</p>
<p class="citation">
<span class="authors">M A Perera, L Cavallari, N Limdi, E Gamazon, A Konkashbaev, R Daneshjou, A Pluzhnikov, D C Crawford, J Wang, N Liu, <strong>NP Tatonetti</strong>, S Bourgeois, H Takahashi, Y Bradford, B M Burkley, R J Desnick, J L Halperin, S I Khalifa, T Y Langaee, S A Lubitz, E A Nutescu, M Oetjens, M H Shahin, S R Patel, H Sagreiya, M Tector, K E Weck, M J Rieder, S A Scott, A HB Wu, J K Burmester, M Wadelius, P Deloukas, M J Wagner, T Mushiroda, M Kubo, D M Roden, N J Cox, R B Altman, T E Klein, Y Nakamura, J A Johnson,</span>
<span class="title">Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.</span>
<span class="journal"><em>The Lancet</em> (2013).</span>
</p>
<p class="citation">
<span class="authors">Ferino G, Cadoni E, Matos MJ, Quezada E, Uriarte E, Santana L, Vilar S, <b>Tatonetti NP</b>, Yanez M, Vina D, Picciau C, Serra S, Delogu G,</span>
<span class="title">MAO Inhibitory Activity of 2‐Arylbenzofurans versus 3‐Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations.</span>
<span class="journal"><em>ChemMedChem</em> (2013).</span>
</p>
<p class="citation">
<span class="authors">S Vilar, E Uriarte, L Santana, <strong>NP Tatonetti</strong>, C Friedman.</span>
<span class="title">Detection of Drug-Drug Interactions by Modeling Interaction Profile Fingerprints.</span>
<span class="journal"><em>PLoS One</em> 8 (3), e58321.</span>
</p>
<p class="citation">
<span class="authors">White RW, <b>Tatonetti NP</b>, Shah NH, Altman RB, Horvitz E,</span>
<span class="title">Web-scale pharmacovigilance: listening to signals from the crowd.</span>
<span class="journal"><i>J Am Med Inform Assoc</i> (2013).</span>
</p>
<p class="citation">
<span class="authors">Matos MJ, Vilar S, Gonzalez-Franco RM, Uriarte E, Santana L, Friedman C, <b>Tatonetti NP</b>, Viña D, Fontenla JA,</span>
<span class="title">Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study.</span>
<span class="journal"><em>European Journal of Medicinal Chemistry</em> 63, 151-161 (2013).</span>
</p>
<span class="author_icon">FA</span>
<p class="citation">
<span class="authors"><strong>Tatonetti NP</strong>, Denny JC, Altman RB,</span>
<span class="title">Response to "Use of an algorithm for identifying hidden drug-drug interactions in adverse event reports" by</span>
<span class="journal">Gooden et al, <em>J Am Med Inform Assoc</em> (2013), doi:10.1136/amiajnl-2012-001603.</span>
</p>
<p class="citation">
<span class="authors">Vilar S, Uriarte E, Santana L, <strong>Tatonetti NP</strong>, Friedman C,</span>
<span class="title">Detection of drug-drug interactions by modeling interaction profile fingerprints.</span>
<span class="journal"><em>PLoS ONE</em> 8, e58321 (2013).</span>
</p>
<p class="citation">
<span class="authors">R Daneshjou, <strong>NP Tatonetti</strong>, KJ Karczewski, H Sagreiya, S Bourgeois, K Drozda, JK Burmester, T Tsunoda, T Nakamura, M Kubo, M Tector, NA Limdi, KH Cavallari, M Perera, JA Johnson, TE Klein, RB Altman</span>
<span class="title">Pathway analysis of genome-wide data improves warfarin dose prediction</span>
<span class="journal"><em>BMC genomics</em> 14 (Suppl 3) S11 2013</span>
</p>
<span class="author_icon">FA</span>
<p class="citation">
<span class="authors"><b>Tatonetti NP</b>, Ye PP, Daneshjou R, Altman RB,</span>
<span class="title">Data-driven prediction of drug effects and interactions.</span>
<span class="journal"><em>Science Translational Medicine</em> 4, 125ra31 (2012).</span>
</p>
<p class="citation">
<span class="authors">Karczewski, KJ, Tirrell RP, Cordero P, <b>Tatonetti NP</b>, Dudley JT, Salari K, Snyder M, Altman RB, Kim SK.</span>
<span class="title">Interpretome: A freely available, modular, and secure personal genome interpretation engine.</span>
<span class="journal"><em>Pac Symp Biocomput</em> 17:339-350(2012)</span>
</p>
<p class="citation">
<span class="authors">Karczewski, K.J. <b>Tatonetti NP</b>, Landt SG, Yang X, Slifer T, Altman RB, Snyder M.</span>
<span class="title">Cooperative transcription factor associations discovered using regulatory variation.</span>
<span class="journal"><em>Proc Natl Acad Sci</em> USA 108, 13353–13358 (2011).</span>
</p>
<span class="author_icon">FA</span>
<p class="citation">
<span class="authors"><b>Tatonetti, N.P.</b>, Fernald, G.H. & Altman, R.B.</span>
<span class="title">A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports.</span>
<span class="journal"><i>J Am Med Inform Assoc</i> (2011) <a href="papers/JAMIA_2011_Tatonetti.pdf">DOI:10.1136/amiajnl-2011-000214</a></span>
</p>
<span class="author_icon">FA</span>
<p class="citation">
<span class="authors"><b>Tatonetti NP</b>, Denny JC, Murphy SN, Fernald GH, Krishnan G, Castro V, P Yue, PS Tsao, Kohane I, Roden DM, and Altman RB.</span>
<span class="title">Detecting Drug Interactions From Adverse-Event Reports: Interaction Between Paroxetine and Pravastatin Increases Blood Glucose Levels</span>
<span class="journal"><i>Clinical Pharmacology & Therapeutics</i> 2011 <a href="papers/CPT_2011_Tatonetti.pdf">DOI:10.1038/clpt.2011.83</a></span>
</p>
<span class="author_icon">FA</span>
<p class="citation">
<span class="authors"><b>Tatonetti NP*</b>, Dudley JT*, Sagreiya H, Butte AJ, Altman RB.</span>
<span class="title">An integrative method for scoring candidate genes from association studies: application to warfarin dosing.</span>
<span class="journal"><i>BMC Bioinformatics</i> 2010 11(Suppl 9):S9. <a href="papers/BMC_Bioinf_2010_Tatonetti.pdf">PMID:21044367</a></span>
</p>
<span class="author_icon">FA</span>
<p class="citation">
<span class="authors">Garten Y*, <b>Tatonetti NP</b>*, Altman RB.</span>
<span class="title">Improving the prediction of pharmacogenes using text-derived drug-gene relationships.</span>
<span class="journal"><em>Pac Symp Biocomput</em> (2010) pp. 305-14. <a href="papers/Pac_Symp_Biocomput_2010_Garten.pdf">PMID:19908383</a></span>
</p>
<span class="author_icon">FA</span>
<p class="citation">
<span class="authors"><b>Tatonetti NP</b>, Liu T, Altman RB.</span>
<span class="title">Predicting drug side-effects by chemical systems biology.</span>
<span class="journal"><em>Genome Biology</em> (2009) vol. 10 (9) pp. 238, <a href="papers/Genome_Biol_2009_Tatonetti.pdf">PMID:19723347</a></span>
</p>
<p>
<i><small>* Denotes equal contribution.</small></i>
</p>
<p class="hide_for_print">
<span class="author_icon" style="float: none; margin-left: 0px; font-size: 10px;">FA</span> First Author Publication
<span class="author_icon" style="float: none; margin-left: 0px; font-size: 10px;">LA</span> Last Author Publication
<span class="author_icon" style="float: none; margin-left: 0px; font-size: 10px;">SA</span> Solo Author Publication
</p>
<br/>
</div>
<!-- FUNDING -->
<h2>Funding Awarded</h2>
<div class="section">
<p>
<i>Data-driven drug discovery: investigating the molecular mechanisms of safety and efficacy</i>
R35 GM131905
National Institute for General Medical Sciences ~$2.5 million (PI: Tatonetti)
</p>
<p>
<i>Clinical and genomic data mining to study pharmacogenomics of drug-induced liver injury</i>
Amgen, Inc. (PI: Tatonetti)
</p>
<p>
<i>Clinical and genomic data mining to study pharmacogenomics of drug-induced liver injury</i>
Amgen, Inc. (PI: Tatonetti)
</p>
<p>
<i>Biomedical Data Translator Technical Feasibility Assessment and Architecture Design</i>
OT3 TR002027
National Center for Advancing Translational Research ~$1.8 million (Contact PI: Tatonetti)
</p>
<p>
<i>Development of an automated clinical informatics system to facilitate genomic discovery</i>
AstraZeneca, Inc (PI: Goldstein, Project Lead: Tatonetti)
</p>
<p>
<i>Genomics of Non-alocholic fatty liver diseae (NAFLD)</i>
Janssen Research & Development, LLC (PI: Wattacheril)
</p>
<p>
<i>Systems Pharmacology to Predict Adverse Drug Reactions</i>
Irving Scholars Program, Irving Institute for Clinical and Translational Research,
Columbia University Medical Center. $180,000 (PI: Tatonetti)
</p>
<p>
<i>Drug Effect Discovery Through Data Mining and Integrative Chemical Biology.</i>
R01 GM107145 National Institute for General Medical Sciences. ~$2.5 million (PI: Tatonetti).
</p>
<p>
<i>Leveraging Big-Data for Drug Discovery in Diseases of Metabolism.</i> PhRMA Foundation Research Starter Award. $100,000 (PI: Tatonetti).
</p>
<p>
<i>WICER 4 U</i> To develop integrative informatics approaches to investigate genetic determinants of clinical outcomes in a longitudinal electronic health records of a community health center. (PI: Bakken, Pilot-Project PI: Tatonetti)
</p>
<p>
<i>High-throughput and computational drug screening.</i> CPS Ignition Grant Application
(PIs: Ali and Tatonetti)
</p>
<p>
<i>Novel Statistical Methods for Observational Clinical Studies</i> Innovation awards in population
medicine research pilot grant. $25,000. (PI: Altman)
</p>
</div>
<!-- SERVICE -->
<h2>Professional Service</h2>
<div class="section">
<p>
External Advisory Panel, Center for Excellence for Natural Product-Drug Interaction Research, 2020-Present
</p>
<p>
Member, Editorial Board, Annual Reviews of Biomedical Data Science, 2020-Present
</p>
<p>
Member, International Scientific Advisor Board, UK Biobank, 2019-Present
</p>
<p>
Special Member, Editorial Board, Annual Reviews of Biomedical Data Science, 2019
</p>
<p>
National Institute on Aging (NIA) U19 Review Committee, 2018
</p>
<p>
Chair, AMIA Summit on Translational Bioinformatics, San Francisco, March 2018
</p>
<p>
Editorial Board Member, Journal of Biomedical Informatics, 2016-2019
</p>
<p>
Honorary Editorial Board Member, Drug Safety, 2015-
</p>
<p>
Vice Chair, AMIA Summit on Translational Bioinformatics, San Francisco, March 2017
</p>
<p>
Track Chair, AMIA Summit on Translational Bioinformatics, San Francisco, March 2016
</p>
<p>
Session Chair, Big Data to Knowledge, AMIA Translational Bioinformatics Meeting, San Francisco, March 2015
</p>
<p>
Session Chair, Big Data to Knowledge, AMIA Translational Bioinformatics Meeting, San Francisco, March 2014
</p>
<p>
Chair, Pre-conference on Next Generation Pharmacology, ASCPT Annual Meeting, March 2014
</p>
<p>
Editorial Board Member, Pharmacology Research & Perspectives, 2013-
</p>
<p>
Scientific Program Committee Member, AMIA Summit on Translational Bioinformatics, 2013, 2014, 2015, 2016
</p>
<p>
Reviewer: Nature, Science, Cell, NEJM, BMJ, Circulation, Nature Medicine, Science Translational Medicine, Cell Systems, Clinical Pharmacology & Therapeutics, CPT:Pharmacometrics & and Systems Pharmacology, PLOS Genetics, PLOS Comp Bio, PLOS One, Molecular Systems Biology, JAMIA, AMIA Symposium, BMC Bioinformatics, Scientific Reports, Journal of Biomedical Informatics, Drug Safety, Database, Allergy, Pacific Symposium on Biocomputing, Bioinformatics
</p>
<p>
NIH Peer Reviewer, Special section on Genome-wide Gene by Environment Interactions
</p>
</div>
<h2>Invited Talks and Panels</h2>
<div class="section">
<p>Invited Speaker, American Society for Human Genetics, Houston, October 15-19, 2019</p>
<p>Keynote Speaker, Health Research Symposium 2019, Hong Kong, June 12, 2019</p>