diff --git a/CHANGELOG.md b/CHANGELOG.md
index f5ce77c05355..ee9305949add 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -17,10 +17,17 @@
   ([#5166](https://github.com/facebook/jest/pull/5166))
 * `[jest-config]` Allow configuration objects inside `projects` array
   ([#5176](https://github.com/facebook/jest/pull/5176))
+* `[expect]` Add support to `.toHaveProperty` matcher to accept the keyPath
+  argument as an array of properties/indices.
+  ([#5220](https://github.com/facebook/jest/pull/5220))
+* `[docs]` Add documentation for .toHaveProperty matcher to accept the keyPath
+  argument as an array of properties/indices.
+  ([#5220](https://github.com/facebook/jest/pull/5220))
 
 ### Chore & Maintenance
 
-* `[docs]` Describe the order of execution of describe and test blocks, and a note on using `test.concurrent`.
+* `[docs]` Describe the order of execution of describe and test blocks, and a
+  note on using `test.concurrent`.
   ([#5217](https://github.com/facebook/jest/pull/5217))
 
 ## jest 22.0.4
diff --git a/docs/ExpectAPI.md b/docs/ExpectAPI.md
index 7efd0ed2554e..9a502c8e0b1b 100644
--- a/docs/ExpectAPI.md
+++ b/docs/ExpectAPI.md
@@ -903,9 +903,10 @@ describe('toMatchObject applied to arrays arrays', () => {
 ### `.toHaveProperty(keyPath, value)`
 
 Use `.toHaveProperty` to check if property at provided reference `keyPath`
-exists for an object. For checking deeply nested properties in an object use
+exists for an object. For checking deeply nested properties in an object you may
+use
 [dot notation](https://developer.mozilla.org/en/docs/Web/JavaScript/Reference/Operators/Property_accessors)
-for deep references.
+or an array containing the keyPath for deep references.
 
 Optionally, you can provide a `value` to check if it's equal to the value
 present at `keyPath` on the target object. This matcher uses 'deep equality'
@@ -943,6 +944,16 @@ test('this house has my desired features', () => {
   ]);
 
   expect(houseForSale).not.toHaveProperty('kitchen.open');
+
+  // Deep referencing using an array containing the keyPath
+  expect(houseForSale).toHaveProperty(['kitchen', 'area'], 20);
+  expect(houseForSale).toHaveProperty(
+    ['kitchen', 'amenities'],
+    ['oven', 'stove', 'washer'],
+  );
+  expect(houseForSale).toHaveProperty(['kitchen', 'amenities', 0], 'oven');
+
+  expect(houseForSale).not.toHaveProperty(['kitchen', 'open']);
 });
 ```
 
diff --git a/packages/expect/src/__tests__/__snapshots__/matchers.test.js.snap b/packages/expect/src/__tests__/__snapshots__/matchers.test.js.snap
index 8b14ee7cf157..f9492e48f432 100644
--- a/packages/expect/src/__tests__/__snapshots__/matchers.test.js.snap
+++ b/packages/expect/src/__tests__/__snapshots__/matchers.test.js.snap
@@ -2562,21 +2562,21 @@ Expected value to have a 'length' property that is a number. Received:
 exports[`.toHaveProperty() {error} expect({"a": {"b": {}}}).toHaveProperty('1') 1`] = `
 "<dim>expect(</><red>object</><dim>)[.not].toHaveProperty(</><green>path</><dim>)</>
 
-Expected <green>path</> to be a string. Received:
+Expected <green>path</> to be a string or an array. Received:
   number: <red>1</>"
 `;
 
 exports[`.toHaveProperty() {error} expect({"a": {"b": {}}}).toHaveProperty('null') 1`] = `
 "<dim>expect(</><red>object</><dim>)[.not].toHaveProperty(</><green>path</><dim>)</>
 
-Expected <green>path</> to be a string. Received:
+Expected <green>path</> to be a string or an array. Received:
   null: <red>null</>"
 `;
 
 exports[`.toHaveProperty() {error} expect({"a": {"b": {}}}).toHaveProperty('undefined') 1`] = `
 "<dim>expect(</><red>object</><dim>)[.not].toHaveProperty(</><green>path</><dim>)</>
 
-Expected <green>path</> to be a string. Received:
+Expected <green>path</> to be a string or an array. Received:
   undefined: <red>undefined</>"
 `;
 
@@ -2616,6 +2616,19 @@ With a value of:
 "
 `;
 
+exports[`.toHaveProperty() {pass: false} expect({"a": {"b": {"c": {"d": 1}}}}).toHaveProperty('a,b,c,d', 2) 1`] = `
+"<dim>expect(</><red>object</><dim>).toHaveProperty(</><green>path</>, <green>value</><dim>)</>
+
+Expected the object:
+  <red>{\\"a\\": {\\"b\\": {\\"c\\": {\\"d\\": 1}}}}</>
+To have a nested property:
+  <green>[\\"a\\", \\"b\\", \\"c\\", \\"d\\"]</>
+With a value of:
+  <green>2</>
+Received:
+  <red>1</>"
+`;
+
 exports[`.toHaveProperty() {pass: false} expect({"a": {"b": {"c": {"d": 1}}}}).toHaveProperty('a.b.c.d', 2) 1`] = `
 "<dim>expect(</><red>object</><dim>).toHaveProperty(</><green>path</>, <green>value</><dim>)</>
 
@@ -2730,6 +2743,31 @@ Received:
   <red>object</>.a: <red>1</>"
 `;
 
+exports[`.toHaveProperty() {pass: false} expect({"a.b.c.d": 1}).toHaveProperty('a.b.c.d', 2) 1`] = `
+"<dim>expect(</><red>object</><dim>).toHaveProperty(</><green>path</>, <green>value</><dim>)</>
+
+Expected the object:
+  <red>{\\"a.b.c.d\\": 1}</>
+To have a nested property:
+  <green>\\"a.b.c.d\\"</>
+With a value of:
+  <green>2</>
+"
+`;
+
+exports[`.toHaveProperty() {pass: false} expect({"a.b.c.d": 1}).toHaveProperty('a.b.c.d', 2) 2`] = `
+"<dim>expect(</><red>object</><dim>).toHaveProperty(</><green>path</>, <green>value</><dim>)</>
+
+Expected the object:
+  <red>{\\"a.b.c.d\\": 1}</>
+To have a nested property:
+  <green>[\\"a.b.c.d\\"]</>
+With a value of:
+  <green>2</>
+Received:
+  <red>1</>"
+`;
+
 exports[`.toHaveProperty() {pass: false} expect({}).toHaveProperty('a') 1`] = `
 "<dim>expect(</><red>object</><dim>).toHaveProperty(</><green>path</><dim>)</>
 
@@ -2774,7 +2812,51 @@ With a value of:
 "
 `;
 
-exports[`.toHaveProperty() {pass: true} expect({"a": {"b": {"c": {"d": 1}}}}).toHaveProperty('a.b.c.d')' 1`] = `
+exports[`.toHaveProperty() {pass: true} expect({"a": {"b": [1, 2, 3]}}).toHaveProperty('a,b,1') 1`] = `
+"<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</><dim>)</>
+
+Expected the object:
+  <red>{\\"a\\": {\\"b\\": [1, 2, 3]}}</>
+Not to have a nested property:
+  <green>[\\"a\\", \\"b\\", 1]</>
+"
+`;
+
+exports[`.toHaveProperty() {pass: true} expect({"a": {"b": [1, 2, 3]}}).toHaveProperty('a,b,1', 2) 1`] = `
+"<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</>, <green>value</><dim>)</>
+
+Expected the object:
+  <red>{\\"a\\": {\\"b\\": [1, 2, 3]}}</>
+Not to have a nested property:
+  <green>[\\"a\\", \\"b\\", 1]</>
+With a value of:
+  <green>2</>
+"
+`;
+
+exports[`.toHaveProperty() {pass: true} expect({"a": {"b": {"c": {"d": 1}}}}).toHaveProperty('a,b,c,d') 1`] = `
+"<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</><dim>)</>
+
+Expected the object:
+  <red>{\\"a\\": {\\"b\\": {\\"c\\": {\\"d\\": 1}}}}</>
+Not to have a nested property:
+  <green>[\\"a\\", \\"b\\", \\"c\\", \\"d\\"]</>
+"
+`;
+
+exports[`.toHaveProperty() {pass: true} expect({"a": {"b": {"c": {"d": 1}}}}).toHaveProperty('a,b,c,d', 1) 1`] = `
+"<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</>, <green>value</><dim>)</>
+
+Expected the object:
+  <red>{\\"a\\": {\\"b\\": {\\"c\\": {\\"d\\": 1}}}}</>
+Not to have a nested property:
+  <green>[\\"a\\", \\"b\\", \\"c\\", \\"d\\"]</>
+With a value of:
+  <green>1</>
+"
+`;
+
+exports[`.toHaveProperty() {pass: true} expect({"a": {"b": {"c": {"d": 1}}}}).toHaveProperty('a.b.c.d') 1`] = `
 "<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</><dim>)</>
 
 Expected the object:
@@ -2808,7 +2890,7 @@ With a value of:
 "
 `;
 
-exports[`.toHaveProperty() {pass: true} expect({"a": {"b": undefined}}).toHaveProperty('a.b')' 1`] = `
+exports[`.toHaveProperty() {pass: true} expect({"a": {"b": undefined}}).toHaveProperty('a.b') 1`] = `
 "<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</><dim>)</>
 
 Expected the object:
@@ -2830,7 +2912,7 @@ With a value of:
 "
 `;
 
-exports[`.toHaveProperty() {pass: true} expect({"a": 0}).toHaveProperty('a')' 1`] = `
+exports[`.toHaveProperty() {pass: true} expect({"a": 0}).toHaveProperty('a') 1`] = `
 "<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</><dim>)</>
 
 Expected the object:
@@ -2852,6 +2934,28 @@ With a value of:
 "
 `;
 
+exports[`.toHaveProperty() {pass: true} expect({"a.b.c.d": 1}).toHaveProperty('a.b.c.d') 1`] = `
+"<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</><dim>)</>
+
+Expected the object:
+  <red>{\\"a.b.c.d\\": 1}</>
+Not to have a nested property:
+  <green>[\\"a.b.c.d\\"]</>
+"
+`;
+
+exports[`.toHaveProperty() {pass: true} expect({"a.b.c.d": 1}).toHaveProperty('a.b.c.d', 1) 1`] = `
+"<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</>, <green>value</><dim>)</>
+
+Expected the object:
+  <red>{\\"a.b.c.d\\": 1}</>
+Not to have a nested property:
+  <green>[\\"a.b.c.d\\"]</>
+With a value of:
+  <green>1</>
+"
+`;
+
 exports[`.toHaveProperty() {pass: true} expect({"property": 1}).toHaveProperty('property', 1) 1`] = `
 "<dim>expect(</><red>object</><dim>).not.toHaveProperty(</><green>path</>, <green>value</><dim>)</>
 
diff --git a/packages/expect/src/__tests__/matchers.test.js b/packages/expect/src/__tests__/matchers.test.js
index 2caec7d65995..bbce3f79d143 100644
--- a/packages/expect/src/__tests__/matchers.test.js
+++ b/packages/expect/src/__tests__/matchers.test.js
@@ -751,6 +751,9 @@ describe('.toHaveLength', () => {
 describe('.toHaveProperty()', () => {
   [
     [{a: {b: {c: {d: 1}}}}, 'a.b.c.d', 1],
+    [{a: {b: {c: {d: 1}}}}, ['a', 'b', 'c', 'd'], 1],
+    [{'a.b.c.d': 1}, ['a.b.c.d'], 1],
+    [{a: {b: [1, 2, 3]}}, ['a', 'b', 1], 2],
     [{a: 0}, 'a', 0],
     [{a: {b: undefined}}, 'a.b', undefined],
     [{a: {b: {c: 5}}}, 'a.b', {c: 5}],
@@ -769,6 +772,9 @@ describe('.toHaveProperty()', () => {
   [
     [{a: {b: {c: {d: 1}}}}, 'a.b.ttt.d', 1],
     [{a: {b: {c: {d: 1}}}}, 'a.b.c.d', 2],
+    [{'a.b.c.d': 1}, 'a.b.c.d', 2],
+    [{'a.b.c.d': 1}, ['a.b.c.d'], 2],
+    [{a: {b: {c: {d: 1}}}}, ['a', 'b', 'c', 'd'], 2],
     [{a: {b: {c: {}}}}, 'a.b.c.d', 1],
     [{a: 1}, 'a.b.c.d', 5],
     [{}, 'a', 'test'],
@@ -789,12 +795,15 @@ describe('.toHaveProperty()', () => {
 
   [
     [{a: {b: {c: {d: 1}}}}, 'a.b.c.d'],
+    [{a: {b: {c: {d: 1}}}}, ['a', 'b', 'c', 'd']],
+    [{'a.b.c.d': 1}, ['a.b.c.d']],
+    [{a: {b: [1, 2, 3]}}, ['a', 'b', 1]],
     [{a: 0}, 'a'],
     [{a: {b: undefined}}, 'a.b'],
   ].forEach(([obj, keyPath]) => {
     test(`{pass: true} expect(${stringify(
       obj,
-    )}).toHaveProperty('${keyPath}')'`, () => {
+    )}).toHaveProperty('${keyPath}')`, () => {
       jestExpect(obj).toHaveProperty(keyPath);
       expect(() =>
         jestExpect(obj).not.toHaveProperty(keyPath),
diff --git a/packages/expect/src/matchers.js b/packages/expect/src/matchers.js
index 4a559412db17..25258e7ef3b2 100644
--- a/packages/expect/src/matchers.js
+++ b/packages/expect/src/matchers.js
@@ -486,7 +486,7 @@ const matchers: MatchersObject = {
     return {message, pass};
   },
 
-  toHaveProperty(object: Object, keyPath: string, value?: any) {
+  toHaveProperty(object: Object, keyPath: string | Array<any>, value?: any) {
     const valuePassed = arguments.length === 3;
 
     if (!object && typeof object !== 'string' && typeof object !== 'number') {
@@ -500,13 +500,17 @@ const matchers: MatchersObject = {
       );
     }
 
-    if (getType(keyPath) !== 'string') {
+    const keyPathType = getType(keyPath);
+
+    if (keyPathType !== 'string' && keyPathType !== 'array') {
       throw new Error(
         matcherHint('[.not].toHaveProperty', 'object', 'path', {
           secondArgument: valuePassed ? 'value' : null,
         }) +
           '\n\n' +
-          `Expected ${EXPECTED_COLOR('path')} to be a string. Received:\n` +
+          `Expected ${EXPECTED_COLOR(
+            'path',
+          )} to be a string or an array. Received:\n` +
           `  ${getType(keyPath)}: ${printReceived(keyPath)}`,
       );
     }